The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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The Effect of Stress on Gastrointestinal Physiology in Irritable Bowel Syndrome

스트레스에 의한 소화 생리학적 변화: 과민성 장증후군 발생과 관련하여

  • Park, Jung-Ho (Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine)
  • 박정호 (성균관대학교 의과대학 강북삼성병원 소화기내과)
  • Published : 2012.02.01
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Abstract

Stress is an acute threat to the homeostasis of an organism by events in the outside world and evokes adaptive responses to preserve the stability of the internal environment. This adaptation can be carried out by means of alterations in HPA axis hormones, the autonomic nervous system, metabolic and immune systems. However, chronic stress can lead to changes in adaptation system and cause a functional disease such as irritable bowel syndrome (IBS). In fact, stress plays an important role in the development and exacerbations of IBS symptoms and it has been postulated that stress have an effect on the pathophysiology of IBS, including an increase in visceral perception, alterations in gastrointestinal motility and increased intestinal permeability. Therefore, Therapeutic approaches targeting stress management could be of great benefit for patients with irritable bowel syndrome.

Keywords

References

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