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Effect of Phosphodiesterase Inhibitor on Diabetic Nephropathy

  • Kang, Shin-Wook (Department of Internal Medicine, Brain Korea 21, Severance Biomedical Science Institute, Yonsei University College of Medicine)
  • 발행 : 2012.06.01

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참고문헌

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  2. Utimura R, Fujihara CK, Mattar AL, Malheiros DM, Noronha IL, Zatz R. Mycophenolate mofetil prevents the development of glomerular injury in experimental diabetes. Kidney Int 2003;63:209-216. https://doi.org/10.1046/j.1523-1755.2003.00736.x
  3. Ehrly AM. Improvement of the flow properties of blood: a new therapeutical approach in occlusive arterial disease. Angiology 1976;27:188-196. https://doi.org/10.1177/000331977602700306
  4. Badri S, Dashti-Khavidaki S, Lessan-Pezeshki M, Abdollahi M. A review of the potential benefits of pentoxifylline in diabetic and non-diabetic proteinuria. J Pharm Pharm Sci 2011;14:128-137. https://doi.org/10.18433/J3BP4G
  5. Chen YM, Lin SL, Chiang WC, Wu KD, Tsai TJ. Pentoxifylline ameliorates proteinuria through suppression of renal monocyte chemoattractant protein-1 in patients with proteinuric primary glomerular diseases. Kidney Int 2006;69:1410-1415. https://doi.org/10.1038/sj.ki.5000302
  6. Sun HK, Lee YM, Han KH, Kim HS, Ahn SH, Han SY. Phosphodiesterase inhibitor improves renal tubulointerstitial hypoxia of the diabetic rat kidney. Korean J Intern Med 2012;27:163-170. https://doi.org/10.3904/kjim.2012.27.2.163
  7. Palm F, Friederich M, Carlsson PO, Hansell P, Teerlink T, Liss P. Reduced nitric oxide in diabetic kidneys due to increased hepatic arginine metabolism: implications for renomedullary oxygen availability. Am J Physiol Renal Physiol 2008;294:F30-F37. https://doi.org/10.1152/ajprenal.00166.2007
  8. dos Santos EA, Li LP, Ji L, Prasad PV. Early changes with diabetes in renal medullary hemodynamics as evaluated by fiberoptic probes and BOLD magnetic resonance imaging. Invest Radiol 2007;42:157-162. https://doi.org/10.1097/01.rli.0000252492.96709.36
  9. Han KH, Han SY, Kim HS, Kang YS, Cha DR. Prolonged administration enhances the renoprotective effect of pentoxifylline via anti-inflammatory activity in streptozotocininduced diabetic nephropathy. Inflammation 2010;33:137-143. https://doi.org/10.1007/s10753-009-9167-6
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