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A Case of Idiopathic Granulomatous Hypophysitis

  • Chung, Chul-Ho (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Song, Min-Soo (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Cho, Hyun-Deuk (Department of Pathology, Soonchunhyang University College of Medicine) ;
  • Jeong, Du-Shin (Department of Neurology, Soonchunhyang University College of Medicine) ;
  • Kim, Yeo-Joo (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Bae, Hack-Gun (Department of Neurosurgery, Soonchunhyang University College of Medicine) ;
  • Kim, Sang-Jin (Department of Internal Medicine, Soonchunhyang University College of Medicine)
  • 발행 : 2012.09.01

초록

Granulomatous hypophysitis is a rare pituitary condition that commonly presents with enlargement of the pituitary gland. A 31-year-old woman was admitted to the hospital with a severe headache and bitemporal hemianopsia. Magnetic resonance imaging (MRI) showed an 18 ${\times}$ 10-mm sellar mass with suprasellar extension and compression of the optic chiasm. Interestingly, brain MRI had shown no abnormal finding 4 months previously. On hormonal examination, hypopituitarism with mild hyperprolactinemia was noted. The biopsy revealed granulomatous changes with multinucleated giant cells. We herein report this rare case and discuss the relevant literature.

키워드

참고문헌

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피인용 문헌

  1. Idiopathic granulomatous hypophysitis: a systematic review of 82 cases in the literature vol.17, pp.4, 2012, https://doi.org/10.1007/s11102-013-0510-4
  2. Idiopathic Granulomatous Hypophysitis: A Rare Cystic Lesion of the Pituitary vol.54, pp.11, 2015, https://doi.org/10.2169/internalmedicine.54.3342
  3. Primary Granulomatous Hypophysitis Presenting with Panhypopituitarism and Central Diabetes Insipidus vol.88, pp.5, 2015, https://doi.org/10.3904/kjm.2015.88.5.581
  4. Idiopathic Granulomatous Hypophysitis Mimicking Pituitary Abscess vol.94, pp.28, 2015, https://doi.org/10.1097/md.0000000000001099
  5. Granulomatous hypophysitis: rare disease with challenging diagnosis vol.5, pp.7, 2017, https://doi.org/10.1002/ccr3.1007
  6. Idiopathic granulomatous hypophysitis: A report of an uncommon disorder vol.61, pp.3, 2012, https://doi.org/10.4103/ijpm.ijpm_77_17
  7. PRIMARY GRANULOMATOUS HYPOPHYSITIS PRESENTING WITH SECONDARY HYPOTHYROIDISM vol.4, pp.4, 2012, https://doi.org/10.4158/accr-2017-0121
  8. Hypophysitis (Including IgG4 and Immunotherapy) vol.110, pp.9, 2012, https://doi.org/10.1159/000506903