The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Hyperamylasemia Associated with Lung Adenocarcinoma

고아밀라제혈증을 보인 폐선암 1예

  • Lee, Myung-Hyun (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Ko, Sun-Young (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Park, Kyun-Woo (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Kim, Jung-Hoon (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Woo, In-Sook (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Han, Chi-Wha (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Heo, Ju-Yeon (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
  • 이명현 (가톨릭대학교 의과대학 내과학교실) ;
  • 고선영 (가톨릭대학교 의과대학 내과학교실) ;
  • 박건우 (가톨릭대학교 의과대학 내과학교실) ;
  • 김정훈 (가톨릭대학교 의과대학 내과학교실) ;
  • 우인숙 (가톨릭대학교 의과대학 내과학교실) ;
  • 한치화 (가톨릭대학교 의과대학 내과학교실) ;
  • 허주연 (가톨릭대학교 의과대학 내과학교실)
  • Published : 2012.04.01
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Abstract

Hyperamylasemia in patients with lung cancer is relatively rare, occurring in 1-3% of all cases of the disease. The pathogenesis of hyperamylasemia in solid cancers is not clear. In Korea, no cases of hyperamylasemia have been reported in patients with adenocarcinoma of the lung. Instead, the lung cancers in patients with hyperamylasemia have in most cases been adenocarcinomas. We report a case of a 64-year-old woman with hyperamylasemia that was suspected to have been induced by mucinous adenocarcinoma of the lung. The patient' amylase isoenzyme pattern was of the salivary type. Systemic chemotherapy normalized her serum amylase levels and produced a partial response in her lung cancer.

종양세포에 의한 혈중 아밀라제의 증가는 드물다고 보고되고 있으며 이소성 아밀라제를 생성하는 종양 중 가장 많은 것은 폐암이며, 그중 조직학적으로 선암이 가장 많은 비중을 차지하고 있다. 국내 보고에서는 고아밀라제 혈증을 동반한 소세포성 폐암 및 편평상피세포 폐암에서의 증례가 각각 한 예씩 있었으나 폐선암에서의 고아밀라제 혈증이 동반된 예는 국내에서 보고된 바가 없어 이를 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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