The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Duodenal Ulcer Perforation Combined with Scrub Typhus

쯔쯔가무시병에 병발된 십이지장 궤양 천공 1예

  • Kang, Jong-Won (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Jeong, Woo-Jin (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Lee, Kyoung-Won (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Lee, Sang-Jin (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Lee, Joung-Hwa (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Kim, Young-Don (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Cheon, Gab-Jin (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine)
  • 강종원 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 정우진 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 이경원 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 이상진 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 이정화 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 김영돈 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 천갑진 (울산대학교 의과대학 강릉아산병원 내과학교실)
  • Published : 2012.04.01
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Abstract

Scrub typhus is an acute febrile illness that results from the destruction of endothelial cells by Orientia tsutsugamushi and subsequent systemic vasculitis. It manifests as fever, headache, myalgia, eschar formation, and lymphadenopathy. Some authors have reported that such vasculitis involves the gastrointestinal tract and that hyperemia, erosion, ulceration, and active bleeding of the gastric mucosa subsequently develop. However, no case of ulcer perforation in a patient with scrub typhus has been reported to date. Here, we report the case of a perforated duodenal ulcer in a 70-year-old female patient with scrub typhus.

쯔쯔가무시병은 O. tustusgamushi에 의한 내피세포 파괴로 전신적인 혈관염이 발생하여 고열, 두통, 근육통, 가피 형성, 림프절 종대가 발생하는 급성 열성 질환이다. 이러한 혈관염이 위장관을 침범하게 되어 위점막에 충혈, 미란, 궤양 그리고 활동성 출혈이 발생하는 증례가 있었으나 궤양에 의한 천공은 지금까지 보고된 예가 없었다. 저자들은 최근에 70세의 여자 환자에서 쯔쯔가무시병에 병발된 십이지장 궤양 천공 1예를 경험하여 보고하는 바이다.

Keywords

References

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Cited by

  1. Duodenal Perforation Precipitated by Scrub Typhus vol.7, pp.2, 2012, https://doi.org/10.4103/0974-777x.154450