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류마티스 관절염 환자에서 슬와부 낭종으로 발현된 칸디다 관절염 1예

Candida Arthritis Presenting as a Huge Popliteal Cyst in a Patient with Rheumatoid Arthritis: A Case Report and Review of the Literature

  • 황현식 (대구가톨릭대학교 의과대학 내과학교실) ;
  • 김현희 (대구가톨릭대학교 의과대학 내과학교실) ;
  • 김홍익 (대구가톨릭대학교 의과대학 내과학교실) ;
  • 백승훈 (대구가톨릭대학교 의과대학 정형외과학교실) ;
  • 박성훈 (대구가톨릭대학교 의과대학 내과학교실) ;
  • 최정윤 (대구가톨릭대학교 의과대학 내과학교실)
  • Hwang, Hyun-Sik (Department of Internal Medicine, Catholic University of Daegu School of Medicine) ;
  • Kim, Hyun-Hee (Department of Internal Medicine, Catholic University of Daegu School of Medicine) ;
  • Kim, Hong-Ik (Department of Internal Medicine, Catholic University of Daegu School of Medicine) ;
  • Baek, Seung-Hoon (Department of Orthopaedic Surgery, Catholic University of Daegu School of Medicine) ;
  • Park, Sung-Hoon (Department of Internal Medicine, Catholic University of Daegu School of Medicine) ;
  • Choe, Jung-Yoon (Department of Internal Medicine, Catholic University of Daegu School of Medicine)
  • 발행 : 2012.01.01

초록

칸디다 관절염은 드문 질환이나 류마티스 관절염 환자와 같은 면역저하자에게 생길 수 있다. 감염 경로는 진균의 직접침범과 혈행을 통한 감염으로 나뉘는데 직접침범의 경우 면역저하자가 관절강내 주사를 맞은 후 또는 관절 수술 후 생길 수 있으며 전신증상 없이 국소 관절부위의 부종, 통증 정도의 증상만 있는 경우가 흔하다. 진단은 관절액 배양검사를 통해 가능하다. 치료는 amphotericin B 정맥주사와 배액이 주로 이용되고 fluconazole 또는 5-fluocytosine을 사용하기도하며 수술적 치료를 시행하는 경우도 있다.

Candida arthritis is an uncommon cause of infectious arthritis that can occur in immunocompromised patients, such as those with rheumatoid arthritis. Candida arthritis arises in two ways: from direct inoculation or hematogenous dissemination. Direct inoculation is common in immunocompromised hosts during intra-articular injection or surgical procedures. The affected joints are generally swollen, tender, and mildly warm, with no evidence of disseminated candidiasis. Reported treatments include intravenous amphotericin B administration and drainage, or the use of 5-fluocytosine or ketoconazole to decrease amphotericin B toxicity. Surgical treatment has been necessary in some cases to eradicate candidal infection. Here, we report a case of candida arthritis combined with a huge popliteal cyst in a patient with rheumatoid arthritis and present a review of the relevant literature.

키워드

참고문헌

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