References
- Smith BW, Adams LA. Non-alcoholic fatty liver disease. Crit Rev Clin Lab Sci 2011;48(3) :97-113. https://doi.org/10.3109/10408363.2011.596521
- Marchesini G, Brizi M, Morselli-Labate AM, Bianchi G, Bugianesi E, McCullough AJ, et al. Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med 1999;107(5) :450-5. https://doi.org/10.1016/S0002-9343(99)00271-5
- Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346(16):1221-31. https://doi.org/10.1056/NEJMra011775
- Sung TS, Son GM. Effect of Cnidi rhizoma boiling extract solution on enzyme and hormone of plasma, and liver in the fatted rats induced by high fat dietary. Korean J Food & Nutrition 1994;7(2):108-13.
- Yun KS, Woo HJ, Lee JH, Kim YC. Effect of Injinchunggan-tang & Injinsaryung-san on NASH induced by MCD-diet in A/J mice. Korean J Orient Int Med 2009;30(2):410-21.
- Choi MY, Woo HJ, Kim YC, Lee JH. Effects of gamisaenggan-tang on high fat diet-induced nonalcoholic fatty liver disease. Korean J Orient Int Med 2009;30(2):365-74.
- Yoo JY, Lee JH. Effects of Saenggantanggami -bang on nonalcoholic fatty liver disease model induced by fatty acids. Korean J Orient Int Med 2010;31(2):143-57.
- Wu JN. An illustrated Chinese materia medica. New York: Oxford University Press; 2005, p. 134.
- Nakashima M, Shigekuni Y, Obi T, Shiraishi M, Miyamoto A, Yamasaki H, et al. Nitric oxide-dependent hypotensive effects of wax gourd juice. J Ethnopharmacol 2011;138(2):404-7. https://doi.org/10.1016/j.jep.2011.09.027
- Huh J. Donguibogam. Seoul: Beobin Press; 1999, p. 745.
- Wang W, Wang WX, Sun BH, Zhao DZ, Gao P. Effect of haidonghua powder(HDHP) on hypothalamic obesity in rats. Zhongguo Zhong yao za zhi 2000;25(8):490-2.
- Huang HY, Huang JJ, Tso TK, Tsai YC, Chang CK. Antioxidant and angiotension-converting enzyme inhibition capacities of various parts of Benincasa hispida (wax gourd). Die Nahrung 2004;48(3):230-3. https://doi.org/10.1002/food.200300428
- Patil RN, Patil RY, Ahirwar B, Ahirwar D. Evaluation of antidiabetic and related actions of some Indian medicinal plants in diabetic rats. Asian Pac J Trop Med 2011;4(1):20-3. https://doi.org/10.1016/S1995-7645(11)60025-4
- Moon MK, Kang DG, Lee YJ, Kim JS, Lee HS. Effect of Benincasa hispida Cogniaux on high glucose-induced vascular inflammation of human umbilical vein endothelial cells. Vascul Pharmacol 2009;50(3-4):116-22. https://doi.org/10.1016/j.vph.2008.11.007
- Park SH, Jeon WK, Kim SH, Kim HJ, Park DI, Cho YK, et al. Prevalence and risk factors of non-alcoholic fatty liver disease among Korean adults. J Gastroenterol Hepatol 2006; 21(1 Pt 1):138-43. https://doi.org/10.1111/j.1440-1746.2005.04086.x
- Marra F, Gastaldelli A, Svegliati Baroni G, Tell G, Tiribelli C. Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis. Trends Mol Med 2008;14(2):72-81. https://doi.org/10.1016/j.molmed.2007.12.003
- Lewis GF, Carpentier A, Adeli K, Giacca A. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 2002;23(2):201-29. https://doi.org/10.1210/er.23.2.201
- Wahren J, Sato Y, Ostman J, Hagenfeldt L, Felig P. Turnover and splanchnic metabolism of free fatty acids and ketones in insulindependent diabetics at rest and in response to exercise. J Clin Invest 1984;73(5):1367-76. https://doi.org/10.1172/JCI111340
- Chen G, Liang G, Ou J, Goldstein JL, Brown MS. Central role for liver X receptor in insulinmediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Proc Natl Acad Sci U S A 2004;101(31):11245-50. https://doi.org/10.1073/pnas.0404297101
- Browning JD, Horton JD. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 2004;114(2):147-52. https://doi.org/10.1172/JCI200422422
- Pettinelli P, Obregon AM, Videla LA. Molecular mechanisms of steatosis in nonalcoholic fatty liver disease. Nutr Hosp 2011;26(3):441-50.
- Bimakr M, Rahman RA, Taip FS, Adzahan NM, Sarker MZ, Ganjloo A. Optimization of Ultrasound-Assisted Extraction of Crude Oil from Winter Melon(Benincasa hispida) Seed Using Response Surface Methodology and Evaluation of Its Antioxidant Activity, Total Phenolic Content and Fatty Acid Composition. Molecules 2012;17(10):11748-62. https://doi.org/10.3390/molecules171011748
- Sabale V, Kunjwani H, Sabale P. Formulation and in vitro evaluation of the topical antiageing preparation of the fruit of Benincasa hispida. J Ayurveda Integr Med 2011;2(3):124-8. https://doi.org/10.4103/0975-9476.85550
- Qadrie ZL, Hawisa NT, Khan MW, Samuel M, Anandan R. Antinociceptive and anti-pyretic activity of Benincasa hispida (thunb.) cogn. in Wistar albino rats. Pak J Pharm Sci 2009; 22(3):287-90.
- Mandal U, De D, Ali KM, Biswas A, Ghosh D. Effect of different solvent extracts of Benincasa hispida T. on experimental hypochlorhydria in rat. J Adv Pharm Technol Res 2012;3(1):41-6.
- Grover JK, Adiga G, Vats V, Rathi SS. Extracts of Benincasa hispida prevent development of experimental ulcers. J Ethnopharmacol 2001; 78(2-3):159-64. https://doi.org/10.1016/S0378-8741(01)00334-8
- Rachchh MA, Jain SM. Gastroprotective effect of Benincasa hispida fruit extract. Indian J Pharmacol 2008;40(6):271-5. https://doi.org/10.4103/0253-7613.45154
- Chandre R, Upadhyay BN, Murthy KH. Clinical evaluation of Kushmanda Ghrita in the management of depressive illness. Ayu 2011; 32(2):230-3. https://doi.org/10.4103/0974-8520.92592
- Dhingra D, Joshi P. Antidepressant-like activity of Benincasa hispida fruits in mice: Possible involvement of monoaminergic and GABAergic systems. J Pharmacol Pharmacother 2012;3(1) :60-2. https://doi.org/10.4103/0976-500X.92521
- Laffitte BA, Chao LC, Li J, Walczak R, Hummasti S, Joseph SB, et al. Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue. Proc Natl Acad Sci U S A 2003;100(9):5419-24. https://doi.org/10.1073/pnas.0830671100
- Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro JM, Shimomura I, et al. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev 2000;14(22):2819-30. https://doi.org/10.1101/gad.844900
- Lee CH, Olson P, Evans RM. Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology 2003;144(6):2201-7. https://doi.org/10.1210/en.2003-0288
- Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Peroxisome proliferator -activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 1999;103(11) :1489-98. https://doi.org/10.1172/JCI6223
- McGarry JD. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 2002;51(1):7-18. https://doi.org/10.2337/diabetes.51.1.7