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Efonidipine, Another Beauty Relieving the Pressure

  • Shin, Jin-Ho (Division of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine)
  • 발행 : 2012.04.30

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참고문헌

  1. Tardif JC. Heart rate as a treatable cardiovascular risk factor. Br Med Bull 2009;90:71-84. https://doi.org/10.1093/bmb/ldp016
  2. Dahlof B, Sever PS, Poulter NR, et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet 2005;366:895-906. https://doi.org/10.1016/S0140-6736(05)67185-1
  3. Williams B, Lacy PS; CAFE and the ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) Investigators. Impact of heart rate on central aortic pressures and hemodynamics: analysis from the CAFE (Conduit Artery Function Evaluation) study: CAFE-Heart Rate. J Am Coll Cardiol 2009;54:705-13. https://doi.org/10.1016/j.jacc.2009.02.088
  4. Komukai M, Tsutsumi T, Ebado M, Takeyama Y. Effect of an L- and T-type calcium channel blocker on 24-hour systolic blood pressure and heart rate in hypertensive patients. Korean Circ J 2012;42:231-8. https://doi.org/10.4070/kcj.2012.42.4.231
  5. Oh IY, Seo MK, Lee HY, et al. Beneficial effect of efonidipine, an L- and T-type dual calcium channel blocker, on heart rate and blood pressure in patients with mild-to-moderate essential hypertension. Korean Circ J 2010;40:514-9. https://doi.org/10.4070/kcj.2010.40.10.514
  6. Sasaki H, Saiki A, Endo K, et al. Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy. J Atheroscler Thromb 2009;16:568-75. https://doi.org/10.5551/jat.1628
  7. Fox K, Ford I, Steg PG, Tendera M, Ferrari R; BEAUTIFUL Investigators. Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. Lancet 2008;372:807-16. https://doi.org/10.1016/S0140-6736(08)61170-8
  8. Tanaka H, Shigenobu K. Efonidipine hydrochloride: a dual blocker of L- and T-type ca(2+) channels. Cardiovasc Drug Rev 2002;20:81-92.