Korean Circulation Journal

  • 제42권7호
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  • Pages.471-478
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  • 2012
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  • 1738-5520(pISSN)
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  • 1738-5555(eISSN)
대한심장학회 (The Korean Society of Cardiology)
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Correlation Between Epicardial Fat Thickness by Echocardiography and Other Parameters in Obese Adolescents

  • Kim, Sung-Jin (Department of Pediatrics, School of Medicine, Ewha Womans University) ;
  • Kim, Hae-Soon (Department of Pediatrics, School of Medicine, Ewha Womans University) ;
  • Jung, Jo-Won (Department of Pediatrics, School of Medicine, Ajou University) ;
  • Kim, Nam-Su (Department of Pediatrics, College of Medicine, Hanyang University) ;
  • Noh, Chung-Il (Department of Pediatrics, College of Medicine, Seoul National University) ;
  • Hong, Young-Mi (Department of Pediatrics, School of Medicine, Ewha Womans University)
  • 발행 : 2012.07.31
⟨ 이전 논문 다음 논문 ⟩

초록

Background and Objectives: Obesity has reached epidemic proportions globally and affects people of all ages. Recent studies have shown that visceral adipose tissue measured by magnetic resonance imaging and/or computed tomography correlates positively with epicardial adipose tissue. Epicardial fat, which is correlated to several metabolic parameters, can be assessed by echocardiography. The aim of this study was to evaluate epicardial fat thickness and other metabolic parameters in obese adolescents and investigate the correlation between epicardial fat thickness and other metabolic parameters in obese adolescents. Subjects and Methods: We selected 99 subjects, between ages 15-17 years of age, to be enrolled in this study. Sixty five obese adolescents with a body mass index (BMI) >95 percentile and 34 control subjects were included in this study. Echocardiographic measurements including epicardial fat thickness as well as anthropometric and blood pressure (BP) measurements were performed. The following parameters were estimated: blood glucose, total cholesterol, triglyceride, high density lipoprotein-cholesterol, low density lipoprotein-cholesterol, aspartate aminotransferase, alanine aminotransferase, free fatty acid, interleukin-6, tumor necrosis factor-${\alpha}$, leptin, adiponectin and high sensitive C reactive protein. Results: The obese group showed a statistically significant correlation with echocardiographic epicardial fat thickness and, BMI, waist circumference, obesity index, fat percentage, systolic BP, insulin level, leptin and adiponectin. Multivariate linear regression analysis showed epicardial fat thickness as the most significant independent parameter to correlate with obese adolescents. Conclusion: These data suggest that epicardial fat thickness measured by echocardiography is a practical and accurate parameter for predicting visceral obesity.

키워드

참고문헌

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