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A Case of Pulmonary Mucormycosis with Necrotizing Pneumonia and Bronchopleural Fistula Cured by Surgical Resection

괴사성 폐렴과 기관지 흉막루가 발생하여 수술로 완치한 폐 털곰팡이증 1예

  • Kim, Hyun-Ju (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Jeon, Hyae-Min (Department of Pathology, Yonsei University College of Medicine) ;
  • Han, Sang-Hoon (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Choi, Jun-Yong (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Song, Young-Goo (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, June-Myung (Department of Internal Medicine, Yonsei University College of Medicine)
  • 김현주 (연세대학교 의과대학 내과학교실) ;
  • 전혜민 (연세대학교 의과대학 병리학교실) ;
  • 한상훈 (연세대학교 의과대학 내과학교실) ;
  • 최준용 (연세대학교 의과대학 내과학교실) ;
  • 송영구 (연세대학교 의과대학 내과학교실) ;
  • 김준명 (연세대학교 의과대학 내과학교실)
  • Published : 2012.09.01

Abstract

Pulmonary mucormycosis is an uncommon opportunistic fungal infection associated with diabetes mellitus, leukemia, lymphoma, and other debilitating diseases. It is diagnosed by the pathologic demonstration of typical hyphae, and the condition requires aggressive surgical treatment to reduce the risk of mortality. Pulmonary mucormycosis is associated with various clinical and radiological characteristics. Therefore, a rapid diagnosis and aggressive surgical approach based on early suspicion are important in high-risk patients in order to cure pulmonary mucormycosis. Here, we report the successful treatment of pulmonary mucormycosis in a 58-year-old male with glottic cancer and uncontrolled diabetes who had rapidly progressive necrotizing pneumonia and a bronchopleural fistula via an aggressive pathologic diagnosis and surgical resection.

전신항암화학요법을 시행 받고 있는 환자에서 당뇨병성 케톤산증으로 인한 의식 소실로 폐렴이 발생하여 광범위한 항균 범위를 갖는 항생제 치료를 시행하였지만 호전되지 않았다. 괴사성 폐렴 및 기관지 흉막루가 발생하여 기관지 내시경을 통한 폐생검으로 폐 털곰팡이증을 진단한 후 항진균제와 적극적인 수술로 완치한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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