The Korean Journal of Medicine

  • 제83권4호
  • /
  • Pages.476-479
  • /
  • 2012
  • /
  • 1738-9364(pISSN)
  • /
  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
권호 표지
DOI QR코드

DOI QR Code

식도 점막하 도관 선종 1예

A Case of Esophageal Submucosal Gland Duct Adenoma

  • 이재곤 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 김대식 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 이지현 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 김민수 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 김윤영 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 황종운 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 심상군 (성균관대학교 의과대학 삼성창원병원 내과)
  • Lee, Jae-Gon (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Changwon Hospital) ;
  • Kim, Dae-Sik (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Changwon Hospital) ;
  • Lee, Ji-Hyun (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Changwon Hospital) ;
  • Kim, Min-Su (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Changwon Hospital) ;
  • Kim, Yun-Young (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Changwon Hospital) ;
  • Hwang, Jong-Woon (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Changwon Hospital) ;
  • Shim, Sang-Goon (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Changwon Hospital)
  • 발행 : 2012.10.01
⟨ 이전 논문 다음 논문 ⟩

초록

식도 점막하 도관 선종은 드문 질환으로 대부분의 식도 선종과는 달리 바렛식도 없이 식도 고유선에서 발생한다. 위내시경을 통한 육안적 검사로는 감별진단이 어려우며 내시경 초음파에서 낭종 외벽이 두껍거나 낭종내 격막이 관찰되면 의심해 볼 수 있다. 특징적인 조직소견은 낭종 내부 도관 상피세포와 외부 근 상피세포로 이루어진 두층 구조를 가진 조직이 증식한다는 점이다. 본 증례는 건강검진에서 우연히 발견된 식도 점막하 병변을 내시경적 절제술을 시행하여 도관 선종을 진단하였고 국내에 보고된 바 없어 문헌고찰과 함께 보고하는 바이다.

An esophageal submucosal gland duct adenoma is a rare benign disease. We report a 58-year-old man who presented with an esophageal submucosal tumor on health screening endoscopy. The endoscopic examination showed a round elevated lesion with central depression at the mid-esophagus. On endoscopic ultrasonography, an anechoic lesion with some hyperechoic septal structures measuring 8 mm in the largest diameter was observed in the third layer. We resected the lesion endoscopically. Histologically, there were several dilated gland ducts, with proliferation of the inner epithelial and outer myoepithelial cell layers. These findings were compatible with a submucosal gland duct adenoma of the esophagus.

키워드

참고문헌

  1. Fockens P, Bartelsman JF, Tytgat GN. Benign and malignant esophageal tumors other than squamous and adenocarcinoma. Gastrointest Endosc Clin N Am 1994;4:791-801.
  2. Rouse RV, Soetikno RM, Baker RJ, Barnard IC, Triadafilopoulos G, Longacre TA. Esophageal submucosal gland duct adenoma. Am J Surg Pathol 1995;19:1191-1196. https://doi.org/10.1097/00000478-199510000-00009
  3. Hopwood D, Coghill G, Sanders DS. Human oesophageal submucosal glands: their detection mucin, enzyme and secretory protein content. Histochemistry 1986;86:107-112. https://doi.org/10.1007/BF00492353
  4. Kawai M. Submucosal gland duct adenoma of the esophagus, report of a case. Stomach Intestine (Tokyo) 2008;43:310-316.
  5. Akinori S, Takaaki M, Chiho O, et al. A case of sialadenoma papilliferum of the esophagus. J Dig Endosc 2005;17: 322-325. https://doi.org/10.1111/j.1443-1661.2005.00554.x
  6. Tsutsumi M, Mizumoto K, Tsujiuchi T, et al. Serous cystadenoma of the esophagus. Acta Pathol Jpn 1990;40: 53-155.
  7. Banducci D, Rees R, Bluett MK, Sawyers JL. Pleomorphic adenoma of the cervical esophagus: a rare tumor. Ann Thorac Surg 1987;44:653-655. https://doi.org/10.1016/S0003-4975(10)62156-X
  8. Agawa H, Matsushita M, Kusumi F, Nishio A, Takakuwa H. Esophageal submucosal gland duct adenoma: characteristic EUS and histopathologic features. Gastrointest Endosc 2003; 57:983-985. https://doi.org/10.1016/S0016-5107(03)70058-3
  9. Endoh Y, Miyawaki M, Tamura G, Watanabe H, Motoyama T. Esophageal adenocarcinoma that probably originated in the esophageal gland duct: a case report. Pathol Int 1999; 9:156-159.