DOI QR코드

DOI QR Code

Investigation of occurrence factors on brucellosis-outbreak farm in Korea

소 브루셀라병 동시 다두 발생 농장의 발생 요인 조사

  • Kim, Ji-Yeon (OIE Reference Laboratory for Brucellosis, Animal, Plant and Fisheries Quarantine & Inspection Agency) ;
  • Kang, Shin-Seok (Chungju Branch, Chungbuk Livestock and Veterinary Research Institute) ;
  • Her, Moon (OIE Reference Laboratory for Brucellosis, Animal, Plant and Fisheries Quarantine & Inspection Agency) ;
  • Lee, Kichan (OIE Reference Laboratory for Brucellosis, Animal, Plant and Fisheries Quarantine & Inspection Agency) ;
  • Sung, So-Ra (OIE Reference Laboratory for Brucellosis, Animal, Plant and Fisheries Quarantine & Inspection Agency) ;
  • Gu, Jung-Hui (OIE Reference Laboratory for Brucellosis, Animal, Plant and Fisheries Quarantine & Inspection Agency) ;
  • Kang, Sung-Il (OIE Reference Laboratory for Brucellosis, Animal, Plant and Fisheries Quarantine & Inspection Agency) ;
  • Lee, Hyang-Keun (OIE Reference Laboratory for Brucellosis, Animal, Plant and Fisheries Quarantine & Inspection Agency) ;
  • Kim, Yu-Jin (OIE Reference Laboratory for Brucellosis, Animal, Plant and Fisheries Quarantine & Inspection Agency) ;
  • Kim, Dong-Gil (OIE Reference Laboratory for Brucellosis, Animal, Plant and Fisheries Quarantine & Inspection Agency) ;
  • Jung, Suk-Chan (OIE Reference Laboratory for Brucellosis, Animal, Plant and Fisheries Quarantine & Inspection Agency)
  • 김지연 (농림수산검역검사본부 동식물위생연구부 세균질병과 브루셀라병 OIE 표준실험실) ;
  • 강신석 (충북 축산위생연구소 북부지소) ;
  • 허문 (농림수산검역검사본부 동식물위생연구부 세균질병과 브루셀라병 OIE 표준실험실) ;
  • 이기찬 (농림수산검역검사본부 동식물위생연구부 세균질병과 브루셀라병 OIE 표준실험실) ;
  • 성소라 (농림수산검역검사본부 동식물위생연구부 세균질병과 브루셀라병 OIE 표준실험실) ;
  • 구정희 (농림수산검역검사본부 동식물위생연구부 세균질병과 브루셀라병 OIE 표준실험실) ;
  • 강성일 (농림수산검역검사본부 동식물위생연구부 세균질병과 브루셀라병 OIE 표준실험실) ;
  • 이향근 (농림수산검역검사본부 동식물위생연구부 세균질병과 브루셀라병 OIE 표준실험실) ;
  • 김유진 (농림수산검역검사본부 동식물위생연구부 세균질병과 브루셀라병 OIE 표준실험실) ;
  • 김동길 (농림수산검역검사본부 동식물위생연구부 세균질병과 브루셀라병 OIE 표준실험실) ;
  • 정석찬 (농림수산검역검사본부 동식물위생연구부 세균질병과 브루셀라병 OIE 표준실험실)
  • Received : 2012.10.23
  • Accepted : 2012.11.23
  • Published : 2012.12.30

Abstract

From the end of July 2012, several cases of abortion have been happened at the Korean indigenous cattle farm with 124 heads in Chungbuk province, Korea. Serological tests such as Rose-bengal test (RBT) and standard tube agglutination test (STAT) have been performed according to the standard official protocols of bovine brucellosis and 41 cattle turned out to be brucellosis-positive simultaneously. To find out the main factors of brucellosis outbreaks and spreads, additional serological, etiological and molecular investigation were applied. Totally, 11 B. abortus were isolated from 10 cattle's specimens including lymph-nodes and/or testis, and drinking water in cowhouse. In genotyping by multi-locus VNTR assay (MLVA) using 17 loci markers, the present B. abortus isolates were shown all the same pattern, D1 genotype, which has been reported in Gyeonggi and Gangwon province, Korea. These results suggest that the input of brucellosis might come from neighboring farms directly or indirectly, even if by unknown factor and expansion within farm would accelerate by materials related with aborting cows.

Keywords

References

  1. Banai M, Corbel M. 2010. Taxonomy of Brucella. The Open Vet Sci J 4: 85-101. https://doi.org/10.2174/1874318801004010085
  2. Her M, Cho DH, Kang SI, Lim JS, Kim HJ, Cho YS, Hwang IY, Lee T, Jung SC, Yoo HS. 2010. Outbreak of brucellosis in domestic elk in Korea. Zoonoses Public Health 57: 155-161. https://doi.org/10.1111/j.1863-2378.2009.01287.x
  3. Her M, Kang SI, Cho DH, Cho YS, Hwang IY, Heo YR, Jung SC, Yoo HS. 2009. Application and evaluation of the MLVA typing assay for the Brucella abortus strains isolated in Korea. BMC Microbiol 9: 230. https://doi.org/10.1186/1471-2180-9-230
  4. Jain N, Boyle SM, Sriranganathan N. 2012. Effect of exogenous erythritol on growth and survival of Brucella. Vet Microbiol 160: 513-516. https://doi.org/10.1016/j.vetmic.2012.06.014
  5. Jung SC, Her M, Kim JW, Kim JY, Hwang IY, Ku BK, Park YH, Yoo HS. 2010. Bovine brucellosis in Korea. J Zoonoses 1: 1-15.
  6. Kang SI, Her M, Kim JW, Kim JY, Ko KY, Ha YM, Jung SC. 2011. Advanced multiplex PCR assay for differentiation of Brucella species. Appl Environ Microbiol 77: 6726-6728. https://doi.org/10.1128/AEM.00581-11
  7. Kim ST, Yoon KB, Kang TK, Bak WH, Lee JH, Chung DS. 2005. Brucellosis outbreak of Korean indigenous cattle at Yeongwol and Pyeongchang county in Korea. Korean J Vet Serv 28: 387-392.
  8. Kim SY, Kim JH, Kim DW. 1999. A serological survey on large outbreak of bovine brucellosis in dairy farm. Korean J Vet Serv 22: 159-167.
  9. Lee BY, Higgins IM, Moon OK, Clegg TA, McGrath G, Collins DM, Park JY, Yoon HC, Lee SJ, More SJ. 2009. Surveillance and control of bovine brucellosis in the Republic of Korea during 2000-2006. Prev Vet Med 90: 66-79. https://doi.org/10.1016/j.prevetmed.2009.03.003
  10. Martirosyan A, Moreno E, Gorvel JP. 2011. An evolutionary strategy for a stealthy intracellular Brucella pathogen. Immunol Rev 240: 211-234. https://doi.org/10.1111/j.1600-065X.2010.00982.x
  11. Meador VP, Deyoe BL. 1989. Intracellular localization of Brucella abortus in bovine placenta. Vet Pathol 26: 513-515. https://doi.org/10.1177/030098588902600609
  12. Nicoletti P. 1980. The epidemiology of bovine brucellosis. Adv Vet Sci Comp Med 24: 69-98.
  13. Park NC, Kim SY, Cho KH, Do JC, Kim YH, Shin SH, Cho MH, Oh KH, Kim WH, Kim JH, Jyeong JS, Kim SW, Kim BH. 1999. Studies on the brucellosis in Kyongbuk area. Korean J Vet Serv 21: 451-465.
  14. Prior MG. 1976. Isolation of Brucella abortus from two dogs in contact with bovine brucellosis. Can J comp Med 40: 117-118.
  15. Ryu JY, Bun JH, Lee HY, Lee YC, Lee JJ, Song YG, Nam HM. 2007. Isolation of Brucella spp from sero-positive native bulls and calves below twelve months old. Korean J Vet Serv 30. 375-384.
  16. Seleem MN, Boyle SM, Sriranganathan N. 2008. Brucella: a pathogen without classic virulence genes. Vet Microbiol 129: 1-14. https://doi.org/10.1016/j.vetmic.2007.11.023
  17. Timoney JF, Gillespie JH, Scott FW, Barlough JE. 1988. Hagan and Bruner's microbiology and infectious diseases of domestic animals. 8ed. pp. 135-152. Cornell University Press, USA.
  18. Troung LQ, Kim JT, Yoon BI, Her M, Jung SC, Hahn TW. 2011. Epidemiological survey for Brucella in wildlife and stray dogs, a cat and rodents captured on farms. J Vet Med Sci 73: 1597-1601. https://doi.org/10.1292/jvms.11-0222
  19. Yang SJ, Shim HS, Woo JT, Kim HS, Lee SS. 2007. Bacteriological detection of Brucella abortus and its characterization by PCR in the sporadic outbreak of bovine brucellosis in Gyeonggi province. Korean J Vet Serv 30: 251-258.
  20. Yoon YB, Kim YJ, Kim CC, Rho YS, Kwon MS, Kim CM, Lim CW. 2004. Epidemiological study for infection route of brucellosis in a infected dairy farms. Korean J Vet Serv 27: 159-164.

Cited by

  1. 국내 가축에서 브루셀라병에 대한 혈청학적 모니터링 vol.54, pp.4, 2014, https://doi.org/10.14405/kjvr.2014.54.4.197
  2. 최근 10년간 국내 소 질병 원인체에 관한 문헌적 고찰 vol.43, pp.3, 2020, https://doi.org/10.7853/kjvs.2020.43.3.113