DOI QR코드

DOI QR Code

오수유부자이중탕(吳茱萸附子理中湯) 및 거풍산(祛風散)으로 발열, 통증, 전신활동도, 두통 호전을 보인 소음인 말초성 T세포 림프종 환자 1례

A Case Study of Soeumin with Peripheral T-cell Lymphoma who Showed Symptomatic Improvement including Fever, Myalgia, Performance Status, and Headache after Treated with Osuyubujaijung-tang and Geopoong-san

  • 최성헌 (경희대학교 한의과대학 강동경희대학교병원 한방암센터) ;
  • 송안나 (경희대학교 한의과대학 강동경희대학교병원 한방암센터) ;
  • 안지혜 (경희대학교 한의과대학 강동경희대학교병원 한방암센터) ;
  • 김은희 (경희대학교 한의과대학 강동경희대학교병원 한방암센터) ;
  • 박소정 (경희대학교 한의과대학 강동경희대학교병원 한방암센터) ;
  • 김경석 (경희대학교 한의과대학 강동경희대학교병원 한방암센터) ;
  • 이수경 (경희대학교 한의과대학 강동경희대학교병원 한방암센터)
  • Choi, Seong-Heon (Cancer Center, Kyung-Hee University hospital at Gangdong, College of Oriental medicine, Kyung-Hee University) ;
  • Song, An-Na (Cancer Center, Kyung-Hee University hospital at Gangdong, College of Oriental medicine, Kyung-Hee University) ;
  • An, Ji-Hye (Cancer Center, Kyung-Hee University hospital at Gangdong, College of Oriental medicine, Kyung-Hee University) ;
  • Kim, Eun-Hee (Cancer Center, Kyung-Hee University hospital at Gangdong, College of Oriental medicine, Kyung-Hee University) ;
  • Park, So-Jeong (Cancer Center, Kyung-Hee University hospital at Gangdong, College of Oriental medicine, Kyung-Hee University) ;
  • Kim, Kyung-Suk (Cancer Center, Kyung-Hee University hospital at Gangdong, College of Oriental medicine, Kyung-Hee University) ;
  • Lee, Soo-Kyung (Cancer Center, Kyung-Hee University hospital at Gangdong, College of Oriental medicine, Kyung-Hee University)
  • 투고 : 2012.11.06
  • 심사 : 2012.12.06
  • 발행 : 2012.12.31

초록

Objectives : The aim of this study was to report the improvement of fever, myalgia, performance status, and headache after treatment with Osuyubujaijung-tang and Geopoong-san in a Soeumin with Peripheral T-cell lymphoma. Methods : We retrospectively reviewed the medical records, medical laboratory and image scans of 80-year-old male patient diagnosed as peripheral T-cell lymphoma. He couldn't conduct any conventional chemotherapy due to poor performance status, ECOG 4. Results : The symptoms of myalgia, poor performance status, and neck pain improved, and fever was reduced with Osuyubujaijung-tang. Headache was subsided with Geopoong-san. Conclusions : A patient with peripheral T-cell lymphoma suffering from fever, myalgia, poor performance status, neck pain and headache showed the improvement of symptoms with treatment of Osuyubujaijung-tang and Geopoong-san. After 4 months treatment, the patient could conduct self care, physical activity and social affairs.

키워드

참고문헌

  1. Chough HS, Jeong YJ, Han JY, Kim HS. A case of peripheral T-cell lymphoma presenting with necrotizing gingival ulcer. Korean J Med. 2010;78(6):766-770. (Korean)
  2. Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982;5(6):649-55. https://doi.org/10.1097/00000421-198212000-00014
  3. Huh J. Epidemiologic overview of malignant lymphoma. Korean J Hematol. 2012;47(2):92-104. (Korean) https://doi.org/10.5045/kjh.2012.47.2.92
  4. Harris NL, Jaffe ES, Diebold J. World Health Organization classification of neoplastic disease of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, Noember 1997. J Clin Oncol. 1999;17:3835- 3849. https://doi.org/10.1200/JCO.1999.17.12.3835
  5. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin. 2012;62:10-29. https://doi.org/10.3322/caac.20138
  6. Vose J, Armitage J, Weisenburger D. International peripheral T-cell and natural killer/T-cell lymphoma study: pathology findings and clinical outocmes. J Clin Oncol. 2008;26:4124-4130. https://doi.org/10.1200/JCO.2008.16.4558
  7. Cadranel J, Wislez M, Antoine M. Primary pulmonary lymphoma. Eur Respir J. 2002;20:750-762. https://doi.org/10.1183/09031936.02.00404102
  8. Dan L. Longo. Malignancies of Lymphoid Cells. In: Anthony S. Fauci, Eugene Braunwald, Dennis L. Kasper, Stephen L. Hauser, Dan L. Longo, J. Larry Jameson, Joseph Loscalzo. Harrison's Principles of Internal Medicine, 17th ed. New York:McGraw-Hill. 2008:687- 700.
  9. Savage KJ, Harris NL, Vose JM. ALK- ana-plastic large-cell lymphoma is clinically and im-munophenotypically different from both ALK+ALCL and peripheral T-cell lymphoma, not other-wise specified: report from the International Pe-ripheral T-Cell Lymphoma Project. Blood.2008;111(12):5496-5504. https://doi.org/10.1182/blood-2008-01-134270
  10. Francine M. Foss, Pier Luigi Zinzani, Julie M. Vose, Randy D. Gascoyne, Steven T. Rosen and Kensei Tobinai. Peripheral T-cell lymphoma. Blood. 2011;117:6756- 6767. https://doi.org/10.1182/blood-2010-05-231548
  11. Abouyabis AN, Shenoy PJ, Flowers C, Lechowicz MJ. Response and survival rates in patients with periph-eral T-cell lymphoma treated with anthracycline-based regimens: a comprehensive meta-analysis [abstract]. Blood. 2007;110(11):Abstract 3452.
  12. Cho HS. Principles and Prescriptionology of Sasang Constitutional medicine. rev. ed. Seoul:Jipmoondang. 2011:276-280. (Korean)
  13. Shin DY, Kim SW, Song JM. A Clinical Study on One Patient Diagnosed as "Soeumin Eumsungkyukyang" as well as Suffering from Atrial Fibrillation. J Sasang Constitut Med. 2004;16(3):114-117. (Korean)
  14. Choi WC, Lee JH, Lee EO, Lee HJ, Yoon SW, Ahn KS, et al. Study on Antiangiogenic and Antitumor Activities of Processed Rhus verniciflua Stokes extract. Korean J. Oriental Physiology & Pathology. 2006;20(4): 825-829. (Korean)
  15. Kim JH, Kim HP, Jung CH, Hong MH, Hong MC, Bae HS, et al. Inhibition of cell cycle progression via p27Kip1 upregulation and apoptosis induction by an ethanol extract of Rhus verniciflua Stokes in AGS gastric cancer cells. Int. J Mol Med. 2006;18(1):201-208,
  16. Lee SJ, Oh PS, Lim K, Lim KT. 36 kDa glycoprotein isolated from Rhus verniciflua Stokes inhibits G/GO-induced mitochondrial apoptotic signal pathways in BNL CL.2 cells. Basic Clin Pharmacol Toxicol. 2005;97(6): 399-405, https://doi.org/10.1111/j.1742-7843.2005.pto_184.x
  17. Jeon WK, Lee JH, Kim HK, Lee AY, Lee SO, Kim YS, et al. Anti-platelet effects of bioactive compounds isolated from the bark of Rhus verniciflua Stokes. J Ethnopharmacol. 2006; 106(1): 62-69, https://doi.org/10.1016/j.jep.2005.12.015
  18. Oh PS, Lee SJ, Lim KT. Hypolipidemic and antioxidative effects of the plant glycoprotein (36 kDa) from Rhus verniciflua Stokes fruit in triton WR-1339- Induced hyperlipidemic mice. Biosci Biotechnol Biochem. 2006;70(2):447-456, https://doi.org/10.1271/bbb.70.447
  19. Choi WC, Jung HS, Kim KS, Lee SK, Yoon SW, Park JH, et al. Rhus verniciflua Stokes against Advanced Cancer: A Perspective from the Korean Integrative Cancer Center. J Biomed Biotechnol. 2012;Article ID 874276:1-7.
  20. Heo DS, Lee KS, Huh JR, Bang YJ, Park SY, Kim CW, et al. Peripheral T-cell lymphomas Presenting as Fever of Unknown Origin. J Korean Cancer Assoc. 1998;30(2):329-337. (Korean)

피인용 문헌

  1. Anticancer Effects of a Korean Herbal Medicine Formula (H9) via AMPK and HER2-PI3K/Akt Signaling in Breast Cancer Cells vol.31, pp.11, 2017, https://doi.org/10.1002/ptr.5906
  2. A Trend Analysis of Case Reports and Case Series on Soeum Person in Journal of Sasang Constitutional Medicine from 2006 to 2015 vol.28, pp.1, 2016, https://doi.org/10.7730/JSCM.2016.28.1.67