DOI QR코드

DOI QR Code

Prevalence of OV Infection in Yasothon Province, Northeast Thailand

  • Saengsawang, Phubet (Department of Epidemiology, Faculty of Public Health, Khon Kaen University) ;
  • Promthet, Supannee (Department of Epidemiology, Faculty of Public Health, Khon Kaen University) ;
  • Bradshaw, Peter (Department of Epidemiology, Faculty of Public Health, Khon Kaen University)
  • 발행 : 2012.07.31

초록

A liver fluke, Opisthorchis viverrrini (OV), is the major cause of the high incidence of cholangiocarcinoma in Thailand. The prevalence of OV infection remains high in various parts of the country, especially in Northeast Thailand and particularly in wetland rural areas where a large proportion of the community work in agriculture and continue the traditional practice of eating raw or uncooked cyprinoid fish products. The national control program seems to have had little impact in many of these areas, and it has been difficult to make precise assessments of the overall effectiveness of the program. This paper is the first report of prospective research project designed to monitor the impact of the national control program in rural communities located in a northeastern province and at high risk of OV infection. The participants in this initial survey were 1,569 villagers, aged 20-65 years, living in two subdistricts of Yasothon Province. Stool examinations showed that 38.68% were infected with OV. Males were slightly more likely to be infected than females, but the difference was not statistically significant. Infection was found to be positively associated with age in both males and females. The preliminary data indicate that the population selected for study is suitable for the purpose of the monitoring project.

키워드

참고문헌

  1. Aunpromma S, Tangkawattana P, Papirom P, et al (2012). High prevalence of Opisthorchis viverrini infection in reservoir hosts in four districts of Khon Kaen Province, an opisthorchiasis endemic area of Thailand. Parasitology International, 61, 60-4. https://doi.org/10.1016/j.parint.2011.08.004
  2. Enes JE, Wages AJ, Malone JB, Tesana S (2010). Prevalence of Opisthorchis viverrini infection in the canine and feline hosts in three villages, Khon Kaen Province, northeastern Thailand. Southeast Asian J Trop Med Publ Health, 41, 36-42.
  3. Grundy-Warr C, Andrews RH, Sithithaworn P, et al (2012). Raw attitudes, wetland cultures, life-styles: Socio-cultural dynamics relating to Opisthorchis viverrini in the Mekong basin. Parasitology Int, 61, 65-70. https://doi.org/10.1016/j.parint.2011.06.015
  4. IARC (1994). Schistosomes, liver flukes and Helicobacterpylori. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, 7-14 June 1994. IARC Monogr Eval Carcinog Risks Hum, 61, 1-241.
  5. Jongsuksuntigul P, Imsomboon T (1998). Epidemiology of opisthorchiasis and national control program in Thailand. Southeast Asian J Trop Med Public Health, 29, 327-32.
  6. Jongsuksuntigul P, Imsomboon T (2003). Opisthorchiasis control in Thailand. Acta Tropica, 88, 229-32. https://doi.org/10.1016/j.actatropica.2003.01.002
  7. Khan SA, Thomas HC, Davidson BR, Taylor-Robinson SD (2005). Cholangiocarcinoma. Lancet, 366, 1303-14. https://doi.org/10.1016/S0140-6736(05)67530-7
  8. Poomphakwaen K, Promthet S, Kamsa-ard S, et al (2009). Risk factors for cholangiocarcinoma in Khon Kaen, Thailand: a nested case-control study. Asian Pac J Cancer Prev, 10, 251-7.
  9. Rhongbutsri P, Kitvatanachai S (2002). Survey of the fluke infection rate in Ban Kok Yai village, Khon Kaen, Thailand. J Trop Med Parasitol, 25, 76-8.
  10. Shin H, Oh J, Masuyer E, Curado M, et al (2010). Epidemiology of cholangiocarcinoma: an update focusing on risk factors. Cancer Sci, 101, 579-85. https://doi.org/10.1111/j.1349-7006.2009.01458.x
  11. Sithithaworn P, Andrews RH, Van De N, et al (2012). The current status of opisthorchiasis and clonorchiasis in the Mekong Basin. Parasitology Int, 61, 10-6. https://doi.org/10.1016/j.parint.2011.08.014
  12. Songserm N, Promthet S, Sithithaworn P, et al (2012) Risk factors for cholangiocarcinoma in high-risk area of Thailand: role of lifestyle, diet and methylenetetrahydrofolate reductase polymmorhisms. Cancer Epidemiology, 36, 89-94. https://doi.org/10.1016/j.canep.2011.04.005
  13. Sriamporn S, Pisani P, Pipitgool V, et al (2004). Prevalence of Opisthorchis viverrini infection and incidence of cholangiocarcinoma in Khon Kaen, Northeast Thailand. Trop Med Int Health, 9, 588-94. https://doi.org/10.1111/j.1365-3156.2004.01234.x
  14. Sripa B, Bethony JM, Sithithaworn P, et al (2011). Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Trop, 120, 158-68. https://doi.org/10.1016/j.actatropica.2010.07.006
  15. Sripa B, Kaewkes S, Sithithaworn P, et al (2007). Liver fluke induces cholangiocarcinoma. PLoS Med, 4, 201. https://doi.org/10.1371/journal.pmed.0040201
  16. Sripa B, Pairojkul C (2008). Cholangiocarcinoma: lessons from Thailand. Curr Opin Gastroenterol, 24, 349-56. https://doi.org/10.1097/MOG.0b013e3282fbf9b3
  17. Watanapa P, Watanapa WB (2002). Liver fluke-associated cholangiocarcinoma. Br J Surg, 89, 962-70. https://doi.org/10.1046/j.1365-2168.2002.02143.x
  18. Wattanayingcharoenchai S, Nithikathkul C, Wonsaroj T, Royal L, Reungsang P (2011). Geographic information system of Opisthorchis viverrini in northeast Thailand. Asian Biomedicine, 5, 687-91.
  19. World Health Organization (1991). Basic laboratory methods in medical parasitology. World Health Organization, Geneva pp 25-8.

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  8. A Comprehensive Public Health Conceptual Framework and Strategy to Effectively Combat Cholangiocarcinoma in Thailand vol.10, pp.1, 2016, https://doi.org/10.1371/journal.pntd.0004293
  9. Cohort profile: cholangiocarcinoma screening and care program (CASCAP) vol.15, pp.1, 2015, https://doi.org/10.1186/s12885-015-1475-7
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