Advances in pediatric surgery
- Volume 18 Issue 1
- /
- Pages.12-17
- /
- 2012
- /
- 2635-8778(pISSN)
- /
- 2635-8786(eISSN)
MRI Findings of Long-term Survivals after Kasai Portoenterostomy
카사이 수술 후 장기생존환자의 간 자기공명영상 소견
- Jung, JiKwang (Department of Pediatric Surgery, Dongsan Medical Center, Keimyung University School of Medicine) ;
- Jung, Eunyoung (Department of Pediatric Surgery, Dongsan Medical Center, Keimyung University School of Medicine) ;
- Park, Woo-Hyun (Department of Pediatric Surgery, Dongsan Medical Center, Keimyung University School of Medicine) ;
-
Choi, Soon-Ok
(Department of Pediatric Surgery, Dongsan Medical Center, Keimyung University School of Medicine)
- 정지광 (계명대학교 의과대학 동산의료원 소아외과) ;
- 정은영 (계명대학교 의과대학 동산의료원 소아외과) ;
- 박우현 (계명대학교 의과대학 동산의료원 소아외과) ;
-
최순옥
(계명대학교 의과대학 동산의료원 소아외과)
- Received : 2012.06.14
- Accepted : 2012.10.10
- Published : 2012.06.30
Abstract
The purpose of this study is to analyse clinical impact of specific MRI findings in liver in patients of long-term survivors after Kasai portoenterostomy (KPE). Twenty-eight patients who were underwent KPE were followed up more than 5 years. Macro-regenerative nodule (MRN) and beaded-duct dilatation (BDD) were considered as important findings in liver MRI. The association between these findings in MRI and clinical indicator, serum bilirubin level and history of cholangitis were evaluated. Sixteen patients (57.1%) were shown MRN in liver MRI. Therewere 14 patients(50%) whose MRI showed BDD. Serum total and direct bilirubin were 3.6 mg/dL and 1.8 mg/dL respectively in positive MRN group whereas 1.4 mg/dL and 0.7 mg/dL in negative MRN group (p = 0.427). Serum total and direct bilirubin level were 4.2 mg/dL and 2.1 mg/dL in patients with BDD negative group compare to 1.1 mg/dL and 0.5 mg/dL in BDD positive group (p = 0.281). The odds ratio to have cholangitis in the patient with MRN was 2.3 and 0.53 in patient with BDD in their MRI findings. MRN in liver MRI may suggest high bilirubin level and more chance to have cholangitis, but the findings of BDD may related to low bilirubin level and less change to have cholangitis.