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이명증 환자 중증도와 삶의 질의 상관 연구

A study on the correlation between health related quality of life(QOL) and the severity of tinnitus patients

  • 서은성 (원광대학교 한의과대학 안이비인후피부과학 교실) ;
  • 황충연 (원광대학교 한의과대학 안이비인후피부과학 교실) ;
  • 임규상 (원광대학교 한의과대학 안이비인후피부과학 교실) ;
  • 강형원 (원광대학교 한의과대학 한방신경정신과학 교실) ;
  • 박민철 (원광대학교 한의과대학 안이비인후피부과학 교실) ;
  • 김남권 (원광대학교 한의과대학 안이비인후피부과학 교실)
  • Seo, Eun-Sung (Ophthalmology Otolaryngology & Dermatology, Wonkwang Univ. Sanbon Oriental Medical Center) ;
  • Hwang, Chung-Yeon (Ophthalmology Otolaryngology & Dermatology, Wonkwang Univ. Sanbon Oriental Medical Center) ;
  • Lim, Kyu-Sang (Ophthalmology Otolaryngology & Dermatology, Wonkwang Univ. Sanbon Oriental Medical Center) ;
  • Kang, Hyuong-Won (Dept. of Neuropsychiatry, Wonkwang Univ. Sanbon Oriental Medical Center) ;
  • Park, Min-Chol (Ophthalmology Otolaryngology & Dermatology, Wonkwang Univ. Sanbon Oriental Medical Center) ;
  • Kim, Nam-Kwen (Ophthalmology Otolaryngology & Dermatology, Wonkwang Univ. Sanbon Oriental Medical Center)
  • 투고 : 2012.10.29
  • 심사 : 2012.11.19
  • 발행 : 2012.11.25

초록

Objective : This study was done to investigate the correlation between general quality of life(QOL) and disease specific QOL of tinnitus patients. Methods : 2009 National health and nutrition survey(NHNS) data were employed for analyzing the mean estimates of total population and tinnitus sub-group patients, and predicting the regression equation of mapping between EQ-5D and disease severity. Baseline statistical analyses and normality tests were done by using Student t-test, Chi-square test, Shapiro-Wilk test and ladder test. Hierarchial regression analyses were performed using related variables and predicted the optimal regression equations. Statistical significance was achieved if the probability was less than 5%. Results : Firstly, the standardized prevalence of tinnitus patient in South Korea was 18.69% and over 90th age-group was relatively higher than other groups. Mean value of domestic QOL measured by EQ-5D was estimated as 0.9486 and QOL of tinnitus subgroup(0.9169) was lower than the non-tinnitus subgroup(0.9559), significantly. Stratified by age and sex, QOLs of all sub-groups with tinnitus were lower than without tinnitus sub-groups significantly. Regression equations from 2009 NHNS data were developed using hierarchial regression analysis which is as follows. $$Y_{EQ-5D}=0.9224-0.0079{\times}T1-0.0261{\times}T2-0.0951{\times}T3+\sum_{i=1}^{n}{\beta}_i{\times}X_i\\{\hspace{95}}(0.0106){\hspace{3}}(0.0037){\hspace{30}}(0.0072){\hspace{30}}(0.0038)$$ ($X_i$=Other explanatory variables except Tinnitus QOL1, 2, 3, ${\beta}$= Regression Coefficient of Model 4) Conclusion : We confirmed the correlation among THI and EQ-5D and HUI-III, and developed the inference for regression equation of EQ-5D.

키워드

참고문헌

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