Bulletin of the Korean Chemical Society

  • 제32권10호
  • /
  • Pages.3581-3586
  • /
  • 2011
  • /
  • 0253-2964(pISSN)
  • /
  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
권호 표지
DOI QR코드

DOI QR Code

Positively Charged Silver Nanoparticles Threaded on Carbon Nanotube for the Efficient Delivery of Negatively Charged Biomolecules

  • Park, Hyung-Seok (Department of Nanobiomedical Science & WCU Research Center, Dankook University Graduate School) ;
  • Hwang, Ji-Young (Institute of Tissue Regeneration Engineering (ITREN), Dankook University) ;
  • Shin, Ueon-Sang (Department of Nanobiomedical Science & WCU Research Center, Dankook University Graduate School) ;
  • Kim, Hae-Won (Department of Nanobiomedical Science & WCU Research Center, Dankook University Graduate School) ;
  • Gong, Myoung-Seon (Department of Nanobiomedical Science & WCU Research Center, Dankook University Graduate School)
  • 투고 : 2011.03.28
  • 심사 : 2011.08.05
  • 발행 : 2011.10.20
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Silver nanoparticle (Ag-NPs)-immobilized and amine-functionalized carbon nanotubes (MWCNTs), MWCNT-Ag-$NH_2$, were easily prepared in order to develop an efficient delivery system of biomolecules without complicated processes of manufacture. For this, Ag-NPs-immobilized MWCNTs, MWCNT-Ag, were initially prepared in order to create large surface area to enable more efficient linkage with guest-molecules using pristine MWCNTs. The Ag-NPs on MWCNTs were further positively functionalized with 2-aminoethanthiol to allow ionic linkage with biomolecules. Ultimately, the positively charged delivery system proved to be highly effective for the binding capacity of bovine serum albumin (BSA) as a negatively charged model protein, when compared to that of lysozyme used as a positively charged model protein. The releasing profile of BSA was observed in almost linear pattern for about two weeks in a saline solution. This study demonstrated the potential usefulness of the pristine MWCNTs in conjunction with Ag-NPs for the selective delivery of many (negatively or positively) charged biomolecules including proteins and genes.

키워드

참고문헌

  1. Baughman, R. H.; Zakhidov, A. A.; de Heer, W. A. Science 2002, 297, 787. https://doi.org/10.1126/science.1060928
  2. Zanello, L. P.; Zhao, B.; Hu, H.; Haddon, R. C. Nano Letters 2006, 6, 562. https://doi.org/10.1021/nl051861e
  3. Foldvari, M.; Bagonluri, M. Nanomedicine 2008, 4, 183. https://doi.org/10.1016/j.nano.2008.04.003
  4. Bahr, J. L.; Yang, J.; Kosynkin, D. V.; Bronikowski, M. J.; Smalley, R. E.; Tour, J. M. J. Am. Chem. Soc. 2001, 123, 6536. https://doi.org/10.1021/ja010462s
  5. Mickelson, E. T.; Huffman, C. B.; Rinzler, A. G.; Smalley, R. E.; Hauge, R. H.; Margrave , J. L. Chem. Phys. Lett. 1998, 296, 188. https://doi.org/10.1016/S0009-2614(98)01026-4
  6. Chen, J.; Hamon, M. A.; Hu, H.; Chen, Y.; Rao, A. M.; Eklund, P. C.; Hadron, R. C. Science 1998, 2, 95.
  7. Yu, B.; Zhou, F.; Liu, G.; Liang, Y.; Huck, W. T. S.; Liu, W. Chem. Commun. 2006, 22, 2356.
  8. Rao, A. M.; Eklund, P. C.; Bandow, S.; Thess, A.; Smalley, R. E. Nature 1997, 388, 257. https://doi.org/10.1038/40827
  9. Penicaud, A.; Poulin, P.; Derre, A.; Anglaret, E.; Petit, P. J. Am. Chem. Soc. 2005, 127, 8. https://doi.org/10.1021/ja0443373
  10. Liu, C. M.; Cao, H. B.; Li, Y. P.; Xu, H. B.; Zhang, Y. Carbon 2006, 44, 2919. https://doi.org/10.1016/j.carbon.2006.05.046
  11. Jung, D. H.; Kim, B. H.; Lim, Y. T.; Kim, J. W.; Lee, S. Y.; Jung, H. T. Carbon 2010, 48, 1070. https://doi.org/10.1016/j.carbon.2009.11.028
  12. Shen, M.; Wang, S. H.; Shi, X.; Chen, X.; Huang, Q.; Elijah, J. P.; Roger, A. P.; James, R. B., Jr.; Walter, J. W., Jr. J. Phys. Chem. C 2009, 113, 3150. https://doi.org/10.1021/jp809323e
  13. Guo, Y.; Guo, S.; Fang, Y.; Dong, S. Electrochimica Acta 2010, 55, 3927. https://doi.org/10.1016/j.electacta.2010.02.024
  14. Arora, S.; Jain, J.; Rajwade, J. M.; Paknikar, K. M. Toxicol. Appl. Pharmacol. 2009, 236, 310. https://doi.org/10.1016/j.taap.2009.02.020
  15. Niu, A.; Han, Y.; Wu, J.; Yu, N.; Xu, Q. J. Phys. Chem. C 2010, 114, 12728. https://doi.org/10.1021/jp104720w
  16. Kalishwaralal, K.; BarathManiKanth, S.; Pandian, S. R. K.; Deepak, V.; Gurunathan, S. J. Control. Release 2010, 145, 76. https://doi.org/10.1016/j.jconrel.2010.03.022
  17. Miura, N.; Shinohara, Y. Biochem. Biophys. Res. Commun. 2009, 390, 733. https://doi.org/10.1016/j.bbrc.2009.10.039
  18. Lewinski, N.; Colvin, V.; Drezek, R. Small 2008, 4, 26. https://doi.org/10.1002/smll.200700595
  19. Gopinath, P.; Gogoi, S. K.; Sanpui, P.; Paul, A.; Chattopadhyay, A. Colloids Surf. B 2010, 77, 240. https://doi.org/10.1016/j.colsurfb.2010.01.033
  20. Wang, J.; Rahman, M. F.; Duhart, H. M.; Newport, G. D.; Patterson, T. A. et al. Neurotoxicology 2009, 30, 926. https://doi.org/10.1016/j.neuro.2009.09.005
  21. Jeon, Y. M.; Cho, H. N.; Gong, M. S. Macromol. Res. 2009, 17, 2. https://doi.org/10.1007/BF03218592
  22. Lim, T. H.; Jeon, Y. M.; Gong, M. S. Polymer (Korea) 2009, 33, 33.
  23. Hong, H. K.; Gong, M. S.; Park, C. K. Bull. Korean Chem. Soc. 2009, 30, 2669. https://doi.org/10.5012/bkcs.2009.30.11.2669
  24. Hong, H. K.; Park, C. K.; Gong, M. S. Bull. Korean Chem. Soc. 2010, 31, 1252. https://doi.org/10.5012/bkcs.2010.31.5.1252
  25. Park, H. S.; Park, H. S.; Gong, M. S. Polymer (Korea) 2010, 34, 144.
  26. Park, H. S.; Park, H. S.; Gong, M. S. Bull. Korean Chem. Soc. 2010, 31, 2575. https://doi.org/10.5012/bkcs.2010.31.9.2575
  27. Park, H. S.; Park, H. S.; Gong, M. S. Macromol. Res. 2010, 18, 897. https://doi.org/10.1007/s13233-010-0913-2
  28. Park, H. S.; Shin, U. S.; Kim, H. W.; Gong, M. S. Bull. Korean Chem. Soc. 2011, 32, 273. https://doi.org/10.5012/bkcs.2011.32.1.273
  29. Hong, H. K.; Shin, U. S.; Kim, H. W.; Gong, M. S. Bull. Korean Chem. Soc. 2011, 32, 1583. https://doi.org/10.5012/bkcs.2011.32.5.1583

피인용 문헌

  1. Facile Preparation of Nanosilver-decorated MWNTs Using Silver Carbamate Complex and Their Polymer Composites vol.33, pp.2, 2012, https://doi.org/10.5012/bkcs.2012.33.2.483
  2. Facile Preparation of Silver Nanoparticles and Application to Silver Coating Using Latent Reductant from a Silver Carbamate Complex vol.34, pp.2, 2011, https://doi.org/10.5012/bkcs.2013.34.2.505
  3. Environmentally Friendly Synthesis: Photocatalytic Dye Degradation and Bacteria Inactivation Using Ag/f-MWCNTs Composite vol.32, pp.3, 2011, https://doi.org/10.1007/s10876-020-01821-8