Delayed Cerebral Metastases from Completely Resected Cardiac Myxoma: Case Report and Review of Literature

완전히 절제된 심장 점액종의 지연된 뇌전이: 증례보고 및 문헌고찰

  • Kim, Ah-Hyun (Department of Radiology, Yonsei University College of Medicine) ;
  • Lee, Jae-Wook (Department of Radiology, NHIC Ilsan Hospital) ;
  • Lee, Mi-Kyung (Department of Pathology, NHIC Ilsan Hospital) ;
  • Yoon, Pyeong-Ho (Department of Radiology, NHIC Ilsan Hospital) ;
  • Kim, Min-Jung (Department of Radiology, Yonsei University College of Medicine)
  • 김아현 (연세대학교 의과대학 세브란스병원 영상의학과) ;
  • 이재욱 (국민건강보험공단 일산병원 영상의학과) ;
  • 이미경 (국민건강보험공단 일산병원 병리과) ;
  • 윤평호 (국민건강보험공단 일산병원 영상의학과) ;
  • 김민정 (연세대학교 의과대학 세브란스병원 영상의학과)
  • Received : 2011.07.25
  • Accepted : 2011.08.24
  • Published : 2011.08.31

Abstract

Cardiac myxoma is the most common benign tumor of the heart. However, low incidence of recurrence and metastasis has been reported. A 49-year-old female patient was admitted in the hospital due to sudden onset of left side weakness. Magnetic resonance imaging (MRI) of brain showed multifocal areas of diffusion restriction on diffusion weighted images. Echocardiography was performed to evaluate the cause of embolic brain infarction and cardiac myxoma was found in the left atrium. The patient underwent complete excision of the mass. One year later, the patient was readmitted with symptoms of dysarthria. Brain MRI showed newly developed multiple hemorrhagic metastatic lesions. The patient underwent radiotherapy of the metastatic lesions. Although rare, cardiac myxoma can cause delayed metastasis. We report a rare case of delayed multiple cerebral metastases from the completely resected cardiac myxoma.

심장점액종은 심장의 가장 흔한 양성 종양이다. 하지만 국소전이와 원격전이의 증례들이 낮은 빈도로 보고되어 있다. 뇌경색을 주소로 내원한 49세 여자 환자의 심장초음파에서 심장 점액종이 발견되었으며 수술로 절제 1년 후에 구음장애가 발생하여 촬영한 자기공명영상에서 여러개의 조영증강이 되는 출혈성뇌전이 병변들이 관찰되었다. 방사선치료 후 추적 자기공명영상에서 병변의 크기들이 작아지는 것을 확인할 수 있었다. 양성 종양이지만 심장 점액종은 드물게 지연되어 전이를 보일 수 있다. 저자들은 심장 점액종을 수술로 완전히 절제 후 지연되어 나타난 뇌전이를 경험하여 증례 및 문헌고찰을 하는 바이다.

Keywords

References

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