Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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A Rapid and Practical Protocol for Solvent-Free Reduction of Oximes to Amines with NaBH4/ZrCl4/Al2O3 System

  • Zeynizadeh, Behzad (Department of Chemistry, Faculty of Science, Urmia University) ;
  • Kouhkan, Mehri (Department of Chemistry, Faculty of Science, Urmia University)
  • Received : 2011.06.13
  • Accepted : 2011.08.01
  • Published : 2011.09.20
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Abstract

Solvent-free reduction of various aldoximes and ketoximes to the corresponding amines was performed easily and efficiently with $NaBH_4$ in the presence of $ZrCl_4$ supported on $Al_2O_3$. The reactions were carried out rapidly (within 2 min) at room temperature to afford the amines in high to excellent yields.

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References

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