Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Three New Iridoid Glucosides from the Roots of Patrinia scabra

  • Di, Lei (Anhui Province Function Laboratory of Resource Use and Development of Traditional Chinese Medicine Materials, School of Life Sciences, Anhui University) ;
  • Li, Ning (Anhui Province Function Laboratory of Resource Use and Development of Traditional Chinese Medicine Materials, School of Life Sciences, Anhui University) ;
  • Zu, Ling-Bo (Anhui Province Function Laboratory of Resource Use and Development of Traditional Chinese Medicine Materials, School of Life Sciences, Anhui University) ;
  • Wang, Kai-Jin (Anhui Province Function Laboratory of Resource Use and Development of Traditional Chinese Medicine Materials, School of Life Sciences, Anhui University) ;
  • Zhao, You-Xing (Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agriculture Sciences) ;
  • Wang, Zhi (Anhui Province Function Laboratory of Resource Use and Development of Traditional Chinese Medicine Materials, School of Life Sciences, Anhui University)
  • Received : 2011.05.31
  • Accepted : 2011.07.16
  • Published : 2011.09.20
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Abstract

To probe the chemical constituents of Patrinia scabra, we undertook the phytochemical investigation on its roots, which led to the isolation and elucidation of three new iridoid glucosides, scabroside A-C (1-3), along with three known iridoids, jatamanin J (4), isopatriscabroside I (5) and loganic acid (6) from the aqueous fraction of the ethanolic extract of the roots. The structures and relative configurations of the three new compounds were elucidated by spectroscopic methods including IR, UV, MS, 1D and 2D NMR experiments. Compound 3 was an unusual iridoid with an oxygen bridge connecting C-3 and C-8.

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References

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