Journal of Environmental Science International (한국환경과학회지)

The Korean Environmental Sciences Society (한국환경과학회)
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Influences of Chitosan, Sericin and Collagen Extract Complexes on the Improvement Actions of Lipid Component in Diabetes

키토산과 세리신 및 콜라겐 추출 혼합물이 당뇨의 혈당 및 지질성분 개선효과

  • Kim, Han-Soo (Department of Food Science & Technology, Pusan National University) ;
  • Jang, Seong-Ho (Department of Bioenvironmental Energy, Pusan National University) ;
  • Yoon, Myung-Joo (Department of Bioenvironmental Energy, Pusan National University) ;
  • Choi, Woo-Seok (Department of Food Science & Technology, Pusan National University) ;
  • Kang, Jin-Soon (School of Food Science, International University of Korea)
  • 김한수 (부산대학교 식품공학과) ;
  • 장성호 (부산대학교 바이오환경에너지학과) ;
  • 윤명주 (부산대학교 바이오환경에너지학과) ;
  • 최우석 (부산대학교 식품공학과) ;
  • 강진순 (한국국제대학교 식품과학부)
  • Received : 2011.05.16
  • Accepted : 2011.07.22
  • Published : 2011.08.31
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Abstract

This study was conducted to examine the influences of chitosan, sericin and collagen extract complexes (1:1:1, w/w/w, CSC-F-005) in blood glucose and lipid concentrations in the sera of streptozotocin (STZ, 55 mg/kg BW, IP injection)-induced diabetic rats (SD strain) fed on experimental diets for 5 weeks. The concentrations of blood glucose, total cholesterol, HDL-cholesterol, ratio of HDL-cholesterol concentration to total cholesterol, atherosclerotic index, LDL-cholesterol, free cholesterol, cholesteryl ester, triglyceride (TG) and phospholipid (PL) in serum were effective on the metabolic regulation in diabetic rats. The activities of alkaline phosphatase (ALP) and aminotransferase (AST, ALT) in serum were lower in the extract complexes (CSC-F-005) than in the diabetic rats. The results shown above suggested that CSC-F-005 extract complexes supplementation effectively improvement of blood glucose and lipid components in the serum of STZ-induced diabetic rats.

Keywords

References

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