Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Comparison of tuberculin skin test with Interferon-γ assay for the diagnosis of bovine tuberculosis in Korean cattle

국내 우군에서 소 결핵 진단을 위한 피내검사법과 Interferon-γ 생성 검사의 비교

  • Shin, Seung Won (College of Veterinary Medicine and BK21 for Veterinary Science, Seoul National University) ;
  • Shin, Min Kyoung (College of Veterinary Medicine and BK21 for Veterinary Science, Seoul National University) ;
  • Cha, Seung Bin (College of Veterinary Medicine and BK21 for Veterinary Science, Seoul National University) ;
  • Woo, Jong Tae (Gyeonggido Veterinary Service) ;
  • Lee, Sung Mo (Incheon Metropolitan City Institute of Health & Environment) ;
  • Ku, Bok Kyung (Bacterial Disease Division, Department of Animal and Plant Health Research, Animal, Plant and Fisheries Quarantine and Inspection Agency) ;
  • Cho, Yun Sang (Bacterial Disease Division, Department of Animal and Plant Health Research, Animal, Plant and Fisheries Quarantine and Inspection Agency) ;
  • Jung, Suk Chan (Bacterial Disease Division, Department of Animal and Plant Health Research, Animal, Plant and Fisheries Quarantine and Inspection Agency) ;
  • Yoo, Han Sang (College of Veterinary Medicine and BK21 for Veterinary Science, Seoul National University)
  • 신승원 (서울대학교 수의과대학 및 BK21 수의과학인력양성사업단) ;
  • 신민경 (서울대학교 수의과대학 및 BK21 수의과학인력양성사업단) ;
  • 차승빈 (서울대학교 수의과대학 및 BK21 수의과학인력양성사업단) ;
  • 우종태 (경기도 축산위생연구소) ;
  • 이성모 (인천광역시 보건환경연구원 가축위생시험소) ;
  • 구복경 (농림수산검역검사본부 동식물위생연구부 세균질병과) ;
  • 조윤상 (농림수산검역검사본부 동식물위생연구부 세균질병과) ;
  • 정석찬 (농림수산검역검사본부 동식물위생연구부 세균질병과) ;
  • 유한상 (서울대학교 수의과대학 및 BK21 수의과학인력양성사업단)
  • Accepted : 2011.06.14
  • Published : 2011.06.30
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Abstract

Bovine tuberculosis (bTB), caused primarily by Mycobacterium bovis, continues to exert an economic loss, even in countries with active control measures, and is one of zoonotic diseases enable to be transmitted to human. The control and eradication of bTB are mainly based on a test and slaughter policy and/or abattoir surveillance. Various factors including limitation of diagnostic tests have been considered as major constraints to eradication. Single intradermal test (SIT) is the official diagnostic test. New diagnostic methods are needed to be developed, because of limitations of the test. In the present study SIT was compared with single intradermal comparative cervical test (SICCT) and interferon (IFN)-${\gamma}$ assay. There was very low correlation between SIT and SICCT. However, high correlation was shown between SIT and IFN-${\gamma}$ assay while no correlation was observed between SICCT and IFN-${\gamma}$ assay. Therefore, our results suggest the possibility of replacement of SIT with IFN-${\gamma}$ assay for the diagnosis of bovine tuberculosis.

Keywords

References

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