Factors Related to Dropout in Clinical Trials of Acupuncture and Moxibustion

침구 임상시험에서의 중도탈락 관련요인

  • Kim, Ae-Ran (Division of Standard Research, Korea Institute of Oriental Medicine) ;
  • Lee, Moo-Sik (Department of Public Health, Graduate School of Public Health and Welfare, Konyang University) ;
  • Hong, Jee-Young (Department of Public Health, Graduate School of Public Health and Welfare, Konyang University)
  • 김애란 (한국한의학연구원) ;
  • 이무식 (건양대학교 보건복지대학원 보건학과) ;
  • 홍지영 (건양대학교 보건복지대학원 보건학과)
  • Received : 2011.06.14
  • Accepted : 2011.07.13
  • Published : 2011.07.30

Abstract

Objective: This study aimed at providing preliminary data useful in reducing participant dropout and improving the quality of clinical trials, by analyzing the factors related to dropout. Methods: The data came from 15 acupuncture and/or moxibustion clinical trials (n=638; August 2005 to December 2009). Logistic regression analysis was used to reveal factors influencing participant dropout. Results: Gender, age, treatment method (intervention), treatment frequency, availability of follow-up, and presence of compensation treatment for the control group were factors influencing participant dropout. Conclusion: Subsequent studies of large-scale acupuncture and moxibustion clinical trials should address dropout factors that consider the character of each clinical trial, or general characters like participants' gender, age, occupation, and diverse diseases.

Keywords

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