The Korean Journal of Mycology (한국균학회지)

The Korean Society of Mycology (한국균학회)
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Stimulatory Effect of Cordyceps militaris on Testosterone Production in Male Mouse

밀리타리스동충하초가 테스토스테론 형성에 미치는 영향

  • Hong, In-Pyo (National Academy of Agricultural Science, Rural Development Administration) ;
  • Choi, Yong-Soo (National Academy of Agricultural Science, Rural Development Administration) ;
  • Woo, Soon-Ok (National Academy of Agricultural Science, Rural Development Administration) ;
  • Han, Sang-Mi (National Academy of Agricultural Science, Rural Development Administration) ;
  • Kim, Hye-Kyung (National Academy of Agricultural Science, Rural Development Administration) ;
  • Lee, Myung-Ryul (National Academy of Agricultural Science, Rural Development Administration) ;
  • Nam, Sung-Hee (National Academy of Agricultural Science, Rural Development Administration) ;
  • Ha, Nam-Gyu (Environment-friendly Agriculture Research Division, Gyeongsangnam-do Agricultural Research & Extension Services)
  • 홍인표 (농촌진흥청 국립농업과학원) ;
  • 최용수 (농촌진흥청 국립농업과학원) ;
  • 우순옥 (농촌진흥청 국립농업과학원) ;
  • 한상미 (농촌진흥청 국립농업과학원) ;
  • 김혜경 (농촌진흥청 국립농업과학원) ;
  • 이명렬 (농촌진흥청 국립농업과학원) ;
  • 남성희 (농촌진흥청 국립농업과학원) ;
  • 하남규 (경상남도농업기술원 친환경연구과)
  • Received : 2011.07.08
  • Accepted : 2011.07.26
  • Published : 2011.08.01
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Abstract

Cordyceps militaris(CM) has been used as a traditional folk medicine to strengthen the immune system and regain energy for hundreds of years in Far East Asian countries. In the present studies, we determined that the stimulatory effect of Cordyceps militaris on testosterone production in male mouse rats. Results illustrated that changes of the body weight, food and water intake of the rats were not observed in this study but the concentration of testosterone in the serum of the rats was significantly increased by CM(p < 0.05). Therefore fruiting bodies of CM grown on the drone bee medium may be an integrative medicine for the treatment of reproductive problems caused by insufficient testosterone levels in human males.

엽산을 다량 함유하고 있는 수벌 번데기와 수벌 번데기에서 생산한 밀리타리스동충하초의 혈청 테스토스테론 상승효과를 확인하기 위하여 실험동물 쥐에 4주간 경구 투여하여 체중변화, 테스토스테론의 수치를 검사하였다. 대조군 및 투여군에서 체중의 증가량은 그룹간, 날짜별 유의적인 차이는 보이지 않았다. 혈청 테스토스테론은 대조군에 비하여 시료를 투여한 모든 군에서 증가경향을 보였다. 더욱이 밀리타리스동충하초 투여구의 호르몬 수치는 대조군에 비하여 통계학적 유의하게 증가하였다.

Keywords

References

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