Renal Adenoma with Hydronephrosis in a Cat

고양이에서 수신증이 동반된 신선종

  • 강상철 (제주대학교 수의과대학) ;
  • 박대식 (사하동물병원) ;
  • 황의경 (상지대학교 생명자원과학대학) ;
  • 우계형 (세명대학교 임상병리학과) ;
  • 김재훈 (제주대학교 수의과대학)
  • Accepted : 2011.06.08
  • Published : 2011.06.30

Abstract

A 6-year-old castrated male domestic short hair cat with the clinical signs of anorexia and vomiting was admitted to the local animal hospital. Abdominal radiography and ultrasonography revealed renomegaly and severe hydronephrosis in the right kidney. Surgically excised right kidney was submitted for diagnosis. On the cut surface, two milky white masses and severe dilation of renal pelvis were observed. Most of the neoplastic masses were composed of uniform well differentiated tubules lined by a single layer of cuboidal to columnar cells and projected papillae into the lumen. The neoplastic cells were strong positive for cytokeratin (CK) MNF116, but negative for CK 7. Based on the clinical and gross findings, histopathology and immunohistochemistry, this case was diagnosed as papillary renal adenoma with hydronephrosis.

식욕부진 및 구토를 동반한 6세령 중성 수컷 고양이(domestic short hair)가 진료를 위해 지역 동물병원에 내원하였다. 복부방사선 및 초음파검사상 우측 신장의 종대 및 심한 수신증 소견을 나타내었다. 외과적으로 적출한 신장에 대하여 병리학적 검사를 실시하였다. 신장 단면절개 시, 2개의 유백색 종괴 및 심한 신우 종대가 확인되었다. 종괴의 대부분은 단일형태의 분화도가 높은 세관 구조로 이루어져 있었으며, 입방 내지 원주형 세포들이 한 층으로 배열되어 있고 내강에 유두상으로 돌출되어 있었다. 면역조직화학기법을 통해 종양세포는 cytokeratin (CK) MNF116에 대하여 강한 양성반응을 보였으나, CK 7에는 음성으로 나타내었다. 따라서 임상증상, 병리학적 소견 및 면역조직화학기법을 통하여 본 증례는 수신증이 동반된 유두상 신선종으로 확진되었다.

Keywords

References

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