Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지

A Study on the Effect of Herbal-acupuncture with Schizandrae Fructus Solution on Hyperlipidemia in Rats Induced by High Fat Diet

양릉천(陽陵泉) 오미자(五味子)약침이 고지방식이로 유발된 고지혈증 흰쥐에 미치는 영향

  • Lee, Sung-Hwan (Department of Acpuncture & Moxibustion, College of Oriental Medecine, Daejon University) ;
  • Lee, Hyun (Department of Acpuncture & Moxibustion, College of Oriental Medecine, Daejon University)
  • 이성환 (대전대학교 한의과대학 침구학교실) ;
  • 이현 (대전대학교 한의과대학 침구학교실)
  • Received : 2011.03.17
  • Accepted : 2011.04.06
  • Published : 2011.04.20
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Abstract

Objectives : The purpose of this study is to observe the effects of herbal acupuncture with Schizandrae Fructus solution at $GB_{34}$(Yangneungcheon) on hyperlipidemia in rats. Methods : In the present study, herbal acupuncture with Schizandrae Fructus solution was administered into hyperlipidemic mice. The author performed several experimental items to analyze the levels of various components and enzymes in serum, liver, as well as the histological changes of liver and aorta. Results : 1. In the Schizandrae Fructus herbal-acupuncture group, serum total cholesterol and Atherogenic index were significantly decreased, and the ratios of HDL to total cholesterol, and phospholipid to total cholesterol in serum were significantly increased as compared with those of the control group. 2. In the Schizandrae Fructus herbal-acupuncture group, HMG-CoA reductase activity was significantly decreased as compared with those of the control group. 3. Schizandrae Fructus herbal-acupuncture reduced deposit of lipid in the liver tissue. Conclusions : From the above results, it is suggested that Schizandrae Fructus herbal-acupuncture at $GB_{34}$ has a therapeutic effect on hyperlipidemia.

Keywords

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