농업과학연구 (Korean Journal of Agricultural Science)

  • 제38권2호
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  • Pages.257-262
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  • 2011
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  • 2466-2402(pISSN)
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  • 2466-2410(eISSN)
충남대학교 농업과학연구소 (Institute of Agricultural Science, CNU)
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한우 FASN 유전자변이와 한우 지방형질 및 지방산조성과의 연관성 분석

Association of genetic polymorphism in fatty acid synthase with BodyFat and fatty acid composition in Hanwoo

  • 이승환 (농촌진흥청 국립축산과학원 한우시험장) ;
  • 김형철 (농촌진흥청 국립축산과학원 한우시험장) ;
  • 조원모 (농촌진흥청 국립축산과학원 한우시험장) ;
  • 장선식 (농촌진흥청 국립축산과학원 한우시험장) ;
  • 김범수 (농촌진흥청 국립축산과학과 동물유전체과) ;
  • 장길원 (농촌진흥청 국립축산과학과 동물유전체과) ;
  • 이준헌 (충남대학교 동물자원생명과학과) ;
  • 연성흠 (농촌진흥청 국립축산과학과 동물유전체과) ;
  • 홍성구 (농촌진흥청 국립축산과학원 한우시험장)
  • Lee, Seung-Hwan (Hanwoo Experiment Station, National Institute of Animal Science, RDA) ;
  • Kim, Hyeong-Cheol (Hanwoo Experiment Station, National Institute of Animal Science, RDA) ;
  • Cho, Won-Mo (Hanwoo Experiment Station, National Institute of Animal Science, RDA) ;
  • Chang, Sun-Sik (Hanwoo Experiment Station, National Institute of Animal Science, RDA) ;
  • Kim, Bum-Soo (Animal Genome& Bioinformatics Division, NIAS, RDA) ;
  • Chang, Gul-Won (Animal Genome& Bioinformatics Division, NIAS, RDA) ;
  • Lee, Jun-Hun (Department of Animal Science & Biotechnology, Chungnam National University) ;
  • Yeon, Seong-Heum (Animal Genome& Bioinformatics Division, NIAS, RDA) ;
  • Hong, Seong-Koo (Hanwoo Experiment Station, National Institute of Animal Science, RDA)
  • 투고 : 2011.04.18
  • 심사 : 2011.06.20
  • 발행 : 2011.06.30
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초록

The aim of this study was to identify the polymorphism on fatty acid synthase (FASN) gene and its association with fat traits and fatty acid composition in Hanwoo. We genotyped a SNP (g.16024G${\rightarrow}$A) detected in Exon34 of FASN on 90 Hanwoo steers by PCR RFLP. A linear mixed model revealed an association of g.16024G${\rightarrow}$A with total body fat contents (P=0.006), while there is no significant effect between g.16024G${\rightarrow}$A and other traits (IMF, BF and fatty acid composition). Regression coefficient and $R^2$ of the SNP was -1.5 kg and 0.36 in this anslysis. Expecially, AA type of g.16024G${\rightarrow}$A bas a less amount of body fat (1.5 kg) than GG type of the SNP in Hanwoo. In conclusion, this study indicates an important role for FASN gene in determining body fat content in Hanwoo.

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참고문헌

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