Tuberculosis and Respiratory Diseases

  • 제71권5호
  • /
  • Pages.335-340
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  • 2011
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  • 1738-3536(pISSN)
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  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
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중증 또는 비전형적 지역사회획득 폐렴으로 입원한 환자에서 호흡기 바이러스의 검출 빈도

Respiratory Virus Detection Rate in Patients with Severe or Atypical Community-acquired Pneumonia

  • 박지원 (가톨릭대학교 대전성모병원 호흡기내과) ;
  • 정선영 (충남대학교 의과대학 내과학교실 호흡기내과) ;
  • 은혁수 (충남대학교 의과대학 내과학교실 호흡기내과) ;
  • 천신혜 (충남대학교 의과대학 내과학교실 호흡기내과) ;
  • 성석우 (충남대학교 의과대학 내과학교실 호흡기내과) ;
  • 박동일 (충남대학교 의과대학 내과학교실 호흡기내과) ;
  • 박명린 (충남대학교 의과대학 내과학교실 호흡기내과) ;
  • 박희선 (충남대학교 의과대학 내과학교실 호흡기내과) ;
  • 정성수 (충남대학교 의과대학 내과학교실 호흡기내과) ;
  • 김주옥 (충남대학교 의과대학 내과학교실 호흡기내과) ;
  • 김선영 (충남대학교 의과대학 내과학교실 호흡기내과) ;
  • 이정은 (충남대학교 의과대학 내과학교실 호흡기내과)
  • Park, Ji-Won (Department of Internal Medicine, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Jung, Sun-Young (Department of Internal Medicine, Chungnam National University College of Medicine) ;
  • Eun, Hyuk-Soo (Department of Internal Medicine, Chungnam National University College of Medicine) ;
  • Cheon, Shin-Hye (Department of Internal Medicine, Chungnam National University College of Medicine) ;
  • Seong, Seok-Woo (Department of Internal Medicine, Chungnam National University College of Medicine) ;
  • Park, Dong-Il (Department of Internal Medicine, Chungnam National University College of Medicine) ;
  • Park, Myung-Rin (Department of Internal Medicine, Chungnam National University College of Medicine) ;
  • Park, Hee-Sun (Department of Internal Medicine, Chungnam National University College of Medicine) ;
  • Jung, Sung-Soo (Department of Internal Medicine, Chungnam National University College of Medicine) ;
  • Kim, Ju-Ock (Department of Internal Medicine, Chungnam National University College of Medicine) ;
  • Kim, Sun-Young (Department of Internal Medicine, Chungnam National University College of Medicine) ;
  • Lee, Jeong-Eun (Department of Internal Medicine, Chungnam National University College of Medicine)
  • 투고 : 2011.05.18
  • 심사 : 2011.09.22
  • 발행 : 2011.11.30
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초록

Background: Community-acquired pneumonia (CAP) is an important cause of morbidity and mortality throughout the world in all age groups. Viral causes of CAP are less well characterized than bacterial causes. We analyzed the characteristics of hospitalized patients with CAP who had a viral pathogen detected by multiplex polymerase chain reaction (PCR). Methods: Multiplex real-time PCR was performed for respiratory viruses in samples collected from 520 adults who developed CAP at Chungnam National University Hospital. Clinical, laboratory, and radiological features at presentation as well as other epidemiological data were analyzed. Results: Of 520 patients with CAP, a viral pathogen was detected in 60 (11.5%), and influenza A was the most common. The virus detection rate in patients with CAP was highest in November. Two or more pathogens were detected in 13 (21.7%) patients. Seven patients had severe disease and were administered in the intensive care unit. Most patients (49/60, 81.7%) had comorbidities. However, nine (15%) patients had no comorbidities, and their age was <60 years. The ground glass opacity pattern was the most common radiological feature. Seven (11.7%) patients died from CAP. Conclusion: Viral pathogens are commonly detected in patients with CAP, and a respiratory virus may be associated with the severity and outcome of pneumonia. Careful attention should be paid to the viral etiology in adult patients with CAP.

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참고문헌

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