Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Trousseau's Syndrome with Catastrophic Course Triggered by an Intravenous Injection

한번의 말초정맥주사로 유발되어 파국적으로 진행된 Trousseau증후군 1예

  • Moon, Ji-Yong (Department of Internal Medicine, Hanil General Hospital, KEPCO Medical Foundation) ;
  • Kim, Sa-Il (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Kwak, Hyun-Jung (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Song, Soon-Young (Department of Radiology, Hanyang University College of Medicine) ;
  • Kim, In-Soon (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Kim, Sang-Heon (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Kim, Tae-Hyung (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Sohn, Jang-Won (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Yoon, Ho-Joo (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Shin, Dong-Ho (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Park, Sung-Soo (Department of Internal Medicine, Hanyang University College of Medicine)
  • 문지용 (의료법인 한전의료재단 한일병원 내과) ;
  • 김사일 (한양대학교 의과대학 내과학교실) ;
  • 곽현정 (한양대학교 의과대학 내과학교실) ;
  • 송순영 (한양대학교 의과대학 영상의학교실) ;
  • 김인순 (한양대학교 의과대학 내과학교실) ;
  • 김상헌 (한양대학교 의과대학 내과학교실) ;
  • 김태형 (한양대학교 의과대학 내과학교실) ;
  • 손장원 (한양대학교 의과대학 내과학교실) ;
  • 윤호주 (한양대학교 의과대학 내과학교실) ;
  • 신동호 (한양대학교 의과대학 내과학교실) ;
  • 박성수 (한양대학교 의과대학 내과학교실)
  • Received : 2011.04.29
  • Accepted : 2011.05.23
  • Published : 2011.08.30
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Abstract

Trousseau's syndrome is an unexplained thrombotic event that precedes the diagnosis of an occult visceral malignancy or appears concomitantly with the tumor. Upper extremity deep vein thrombosis is prevalent in patients with a central venous catheter. Furthermore, a peripheral intravenous injection may cause upper extremity deep vein thrombosis as well. However, a deep vein thrombosis has not been reported in the form of Trousseau's syndrome with a catastrophic clinical course triggered by a single peripheral intravenous injection. A 48-year-old man presented with a swollen left arm on which he was given intravenous fluid at a local clinic due to flu symptoms. Contrast computed tomgraphy scans showed thromboses from the left distal brachial to the innominate vein. The patient developed multiple cerebral infarctions despite anticoagulation treatment. He was diagnosed with stomach cancer by endoscopic biopsy to evaluate melena and had a persistently positive lupus anticoagulant. After recurrent and multiple thromboembolic events occurred with treatment, he died on day 20.

Keywords

References

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