Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Cranial Nerve Palsy as a Paraneoplastic Syndrome in Non-Small Cell Lung Cancer

비소세포폐암 환자에서 부종양성 증후군의 증상으로 발생한 좌측 3, 4 뇌신경마비 1예

  • Lee, Young-Mi (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Sim, Woo-Ho (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Yoon, Sun-Och (Department of Pathology, Yonsei University College of Medicine) ;
  • Kim, Song-Yee (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Jung-Soo (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kho, Bo-Gun (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Byun, Min-Kwang (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Choi, Young-Chul (Department of Neurology, Yonsei University College of Medicine) ;
  • Kim, Hyung-Jung (Department of Internal Medicine, Yonsei University College of Medicine)
  • 이영미 (연세대학교 의과대학 내과학교실) ;
  • 심우호 (연세대학교 의과대학 내과학교실) ;
  • 윤선옥 (연세대학교 의과대학 병리학교실) ;
  • 김송이 (연세대학교 의과대학 내과학교실) ;
  • 박정수 (연세대학교 의과대학 내과학교실) ;
  • 고보건 (연세대학교 의과대학 내과학교실) ;
  • 변민광 (연세대학교 의과대학 내과학교실) ;
  • 최영철 (연세대학교 의과대학 신경과학교실) ;
  • 김형중 (연세대학교 의과대학 내과학교실)
  • Received : 2010.08.12
  • Accepted : 2010.10.18
  • Published : 2011.02.28
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Abstract

Paraneoplastic neurologic syndrome is a group of assorted disorders resulting from damage to the nervous system in cancer, remote from primary site, and not related to metastasis, infection, or metabolic disorder associated with cancer. Patient with small cell lung cancer sometimes shows various neurological syndromes, but patient with non-small cell lung cancer rarely shows neurologic syndromes and few antineuronal antibodies have been found. Here, we report a case of 53-year-old male patient who developed ptosis and extraocular muscular limitation of left eye due to third and forth cranial nerve palsy in non-small cell lung cancer without brain metastasis. These neurologic symptoms improved after lobectomy without any other treatment immunotherapy.

Keywords

References

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