A Case of an Imported Dengue Hemorrhagic Fever with Spontaneous Bleeding: Case Report and Review of the Literature

자발성 출혈을 동반한 뎅기출혈열 1례

  • Choi, Hyun Hyi (Department of Family Medicines, Busan Paik Hospital, Inje University College of Medicine) ;
  • Park, Jeong A (Department of Pediatrics, Haeundae Paik Hospital, Inje University College of Medicine) ;
  • Kim, Jun Soo (Department of Family Medicines, Busan Paik Hospital, Inje University College of Medicine) ;
  • Hur, Yun Jung (Department of Pediatrics, Haeundae Paik Hospital, Inje University College of Medicine) ;
  • Song, Min Seop (Department of Pediatrics, Haeundae Paik Hospital, Inje University College of Medicine) ;
  • Hwang, Tae Gyu (Department of Pediatrics, Haeundae Paik Hospital, Inje University College of Medicine) ;
  • Choi, Yong (Department of Pediatrics, Haeundae Paik Hospital, Inje University College of Medicine)
  • 최현희 (부산백병원 가정의학과) ;
  • 박정아 (해운대 백병원 소아청소년과) ;
  • 김준수 (부산백병원 가정의학과) ;
  • 허윤정 (해운대 백병원 소아청소년과) ;
  • 송민섭 (해운대 백병원 소아청소년과) ;
  • 황태규 (해운대 백병원 소아청소년과) ;
  • 최용 (해운대 백병원 소아청소년과)
  • Received : 2011.04.26
  • Accepted : 2011.06.07
  • Published : 2011.12.25

Abstract

Dengue is an acute febrile viral disease which is found in tropical and sub-tropical regions around the world. Dengue fever has steadily increased in both incidence and distribution over the past 50 years. Even though Korea is not an endemic country for dengue fever, with the increasing numbers of overseas travelers in Korea, the numbers of imported dengue cases are steadily increasing. Here, we report a case of imported dengue hemorrhagic fever in a Korean child presenting with fever and epistaxis. Dengue fever should be considered if a patient who has a recent travel history to endemic areas showed classical symptoms.

뎅기열은 열대와 아열대지역에서 호발하며, Aedes aegypti 모기에 의해 전파되는 바이러스성 급성 발열 질환이다. 뎅기열은 발열과 인플루엔자 유사증상, 피부발진으로 특징지어지며, 뎅기출혈열의 경우 발열과 출혈증상, 혈장삼출 등을 동반하며, 심한 경우 혈장삼출에 의한 저혈량성 쇼크가 발생할 수 있고, 이를 뎅기쇼크증후군이라 하며 적절한 치료가 없을 경우 사망까지 이를 수 있다. 국내에서는 뎅기열의 발생빈도가 낮아 접하기가 쉽지 않고, 따라서 감별진단으로 고려하기 어려운 점이 있다. 저자들은, 11개월간 유학생으로 필리핀에 거주하였던 14세 남아가 뎅기출혈열로 진단된 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

  1. World Health Organization: Dengue and dengue hemorrhagic fever. Available from: http://www.who.int/csr/disease/dengue/en/
  2. Korea Centers for Disease Control and Prevention. Imported dengue cases in Korea. Public Health Weekly Report. 2008 Jul 4;1(14)
  3. Disease web statistics system: Dengue fever. Korea Centers for Disease Control and Prevention. Available from: http://cdc.go.kr/kcdchome/
  4. Choi SH, Kim YJ, Shin JH, Yoo KH, Sung KW, Koo HH. International travel of Korean children and Dengue fever: A single institutional analysis. Korean J Pediatr 2010;53:701-4. https://doi.org/10.3345/kjp.2010.53.6.701
  5. Chung MH. Dengue fever. Korean J Med 2009;77:165-70.
  6. Thavara U, Tawatsin A, Chansang C, Kongngamsuk W, Paosriwong S, Boon-Long J, et al. Larval occurrence, oviposition behavior and biting activity of potential mosquito vectors of dengue on Samui Island, Thailand. J Vector Ecol 2001;26:172-80.
  7. Morens DM. Dengue Fever and dengue hemorrhagic Fever. Pediatr Infect Dis J 2009;28:635-6. https://doi.org/10.1097/INF.0b013e3181afcd5b
  8. Srikiatkhachorn A, Krautrachue A, Ratanaprakarn W, Wongtapradit L, Nithipanya N, Kalayanarooj S, et al. Natural history of plasma leakage in dengue hemorrhagic fever: a serial ultrasonic study. Pediatr Infect Dis J 2007;26:283-90. https://doi.org/10.1097/01.inf.0000258612.26743.10
  9. Halstead SB. Dengue. Lancet 2007;370:1644-52. https://doi.org/10.1016/S0140-6736(07)61687-0
  10. Pincus LB, Grossman ME, Fox LP. The exanthem of dengue fever: Clinical features of two US tourists traveling abroad. J Am Acad Dermatol 2008;58:308-16. https://doi.org/10.1016/j.jaad.2007.08.042
  11. Watt G, Jongsakul K, Chouriyagune C, Paris R. DIfferentiating dengue virus infection from scrub typhus in Thai adults with fever. Am J Trop Med Hyg 2003;68:536-8. https://doi.org/10.4269/ajtmh.2003.68.536
  12. Singhi S, Kissoon N, Bansal A. Dengue and dengue hemorrhagic fever: management issues in an intensive care unit. J Pediatr 2007;83:22-35. https://doi.org/10.2223/JPED.1622
  13. Choi SH, Kim YJ, Shin JH, Yoo KH, Sung KW, Koo HH. International travel of Korean children and Dengue fever: A single institutional analysis. Korean J Pediatr 2010;53:701-4. https://doi.org/10.3345/kjp.2010.53.6.701