Pediatric Infection and Vaccine

  • 제18권2호
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  • Pages.117-123
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  • 2011
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  • 2384-1079(pISSN)
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  • 2384-1087(eISSN)
대한소아감염학회 (The Korean Society of Pediatric Infectious Diseases)
권호 표지

국내 홍역, 유행성이하선염 및 풍진 백신 접종 후 연령에 따른 항체양성율 변화

The Change of IgG Antibody Titer to Measles, Mumps and Rubella According to Age

  • 방성준 (관동대학교 의과대학 소아청소년과) ;
  • 최경민 (관동대학교 의과대학 소아청소년과)
  • Pang, Sung Joon (Department of Pediatrics, Kwandong University College of Medicine) ;
  • Choi, Kyong Min (Department of Pediatrics, Kwandong University College of Medicine)
  • 투고 : 2011.09.26
  • 심사 : 2011.10.10
  • 발행 : 2011.12.25
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초록

목 적: 홍역, 유행성이하선염 및 풍진 예방접종 시행후 연령 증가에 따른 항체양성율의 변화를 조사한다. 방 법: 병원에 내원한 7-20세의 환아를 대상으로 잔여 혈청을 이용하여 IgG 항체를 검사하였다. 결 과: 총 408례 중 홍역은 275례로 67.4%, 유행성이하선염은 112례로 27.5%, 풍진은 367례로 90.0%의 양성율을 보였다. 양성자의 IgG 수치는 각각 $2.77{\pm}1.18$ Index, $2.08{\pm}1.29$ Index 및 $60.46{\pm}63.47$ IU/mL 이었다. 결 론: 홍역 67.4%, 유행성이하선염 27.5% 및 풍진 90.0%의 IgG 항체 양성율을 보였다. 홍역, 유행성이하선염 및 풍진의 유행을 막기 위해서는 높은 접종율의 유지가 중요하며, 또한 보호자에 대한 접종기록 등의 관리가 중요할 것으로 생각된다.

Purpose : We investigated the change of antibody titer to measles, mumps and rubella according to age after vaccination. Methods : The IgG antibody titers to measles, mumps and rubella were tested on the residual serum from patients aged 7-20 years old after routine laboratory testing in the hospital with informed consent from the parents. Results : Antibody to measles was present in 275 cases out of 408 cases with a positive rate of 67.4%, the mean IgG titer was 2.77${\pm}$1.18 Index. Antibody to mumps was present in 112 cases out of 408 cases with a positive rate of 27.5%, the mean IgG titer was 2.08${\pm}$1.29 Index. Antibody to rubella was present in 367 cases out of 408 cases with a positive rate of 90.0%, the mean IgG titer was 60.46${\pm}$63.47 IU/mL. Conclusion : It is important to maintain a high rate of vaccination coverage in order to prevent an outbreak of measles, mumps, or rubella. It is also important to stress the maintenance of vaccination records for further reference.

키워드

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