Parasites, Hosts and Diseases

  • 제49권1호
  • /
  • Pages.73-77
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  • 2011
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  • 2982-5164(pISSN)
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  • 1738-0006(eISSN)
대한기생충학·열대의학회 (The Korea Society for Parasitology and Tropical Medicine)
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A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel

  • Kyung, Sun-Young (Department of Medicine, Gachon University Gil Medical Center) ;
  • Cho, Yong-Kyun (Department of Medicine, Gachon University Gil Medical Center) ;
  • Kim, Yu-Jin (Department of Medicine, Gachon University Gil Medical Center) ;
  • Park, Jeong-Woong (Department of Medicine, Gachon University Gil Medical Center) ;
  • Jeong, Sung-Hwan (Department of Medicine, Gachon University Gil Medical Center) ;
  • Lee, Jae-Ik (Department of Thoracic Surgery, Gachon University Gil Medical Center) ;
  • Sung, Yon-Mi (Department of Radiology, Gachon University Gil Medical Center) ;
  • Lee, Sang-Pyo (Department of Medicine, Gachon University Gil Medical Center)
  • 투고 : 2010.09.06
  • 심사 : 2010.12.11
  • 발행 : 2011.03.15
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초록

Paragonimiasis is an infectious disease caused by trematodes of the genus Paragonimus. This trematode can be treated successfully with praziquantel in more than 90% of the cases. Although praziquantel is generally well tolerated, anaphylactic reactions to this drug have been reported in a few cases. We report here a 46-year-old Korean female with paragonimiasis, presumed to be due to Paragonimus westermani, who displayed an allergic reaction to praziquantel and resistance to triclabendazole treatment. The patient was successfully treated with praziquantel following a rapid desensitization procedure. Desensitization to praziquantel could be considered when no alternative drugs are available.

키워드

참고문헌

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  10. Effects of Three-time Administration of a Supramolecular Complex of Praziquantel with Disodium Glycyrrhizinate on Trematode Opisthorchis felineus in Hamsters vol.66, pp.2, 2021, https://doi.org/10.1007/s11686-020-00329-5