Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics (대한후두음성언어의학회지)

The Korean Society of Laryngology, Phoniatrics and Logopedics. (대한후두음성언어의학회)
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A Case of Malignant Fibrous Histiocytoma of the Larynx

후두에 발생한 악성 섬유성 조직구종

  • Koo, Yong-Cheol (Department of Otorhinolaryngology, Yonsei University College of Medicine) ;
  • Hwang, Chi-Sang (Department of Otorhinolaryngology, Yonsei University College of Medicine) ;
  • Kim, Gi-Jeong (Department of Pathology, Yonsei University College of Medicine) ;
  • Choi, Hong-Shik (Department of Otorhinolaryngology, Yonsei University College of Medicine)
  • 구용철 (연세대학교 의과대학 이비인후과학교실) ;
  • 황치상 (연세대학교 의과대학 이비인후과학교실) ;
  • 김기정 (연세대학교 의과대학 병리학교실) ;
  • 최홍식 (연세대학교 의과대학 이비인후과학교실)
  • Received : 2011.11.30
  • Accepted : 2012.01.06
  • Published : 2011.12.01
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Abstract

Malignant fibrous histiocytoma is one of the rare types of larynx tumor. The most common sites of the tumor are limbs, trunk, and retroperitoneal space, but tumor localization within head and neck are very rare. It is built of histiocytes, fibroblasts and multinuclear giant cells. A diagnosis of the tumor includes microscopic and immunohistologic examination with identification of specific tissue markers and intermediate filaments of proteins. This disease has been treated by several methods combining radical surgery, radiotherapy, and chemotherapy, but the prognosis is poor. We present 74-year-old Asian man with dysphonia for 2 years. The tumor of the larynx was examined on laryngoscopy. The radical surgery rendered the final pathological diagnosis, confirmed histologically and immunohistochemically as malignant fibrous histiocytoma. This tumor was treated with laser cordectomy followed by radiotherapy. 3.5 year's observation of the patient didn't either show any signs of recurrence or dysphonia.

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