Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Lymphoplasmacytic Gingivitis in 3 Cats

고양이의 림프구형질세포성 치은염 증례

  • Yoon, Jeong-Sik (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Jung, Ji-Youl (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Park, Woon-Keun (YongKang Animal Hospital) ;
  • Lee, Jong-Hoon (YongKang Animal Hospital) ;
  • Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
  • 윤정식 (제주대학교 수의과대학 및 수의과학연구소) ;
  • 정지열 (제주대학교 수의과대학 및 수의과학연구소) ;
  • 김재훈 (제주대학교 수의과대학 및 수의과학연구소) ;
  • 박원근 (용강동물병원) ;
  • 이종훈 (용강동물병원) ;
  • 김재훈 (제주대학교 수의과대학 및 수의과학연구소)
  • Accepted : 2010.10.04
  • Published : 2011.02.28
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Abstract

Three cats with 2 weeks to 1 month history of drooling, halitosis, difficulty eating and pain on opening the mouth were presented to local animal hospitals. On physical examination, the gingiva was swollen, bright red and very painful with bilaterally symmetric pattern. Surgically excised abnormal gingival biopsy samples were requested for diagnosis. Histopathologically, gingival epithelium showed severe hyperplasia and ballooning degeneration. Moderate to severe infiltration of lymphocytes and plasma cells were presented in lamina propria. Immunohistochemically, inflammatory cells of the samples demonstrated major positive reactions for T lymphocytes. But some plasma cells also presented. According to polymerase chain reaction, tissues samples were negative for four kinds of feline viral pathogens. Based on the clinical, gross, histopathologic findings, these three cases were diagnosed as lymphoplasmacytic gingivitis in cats. In our best knowledge, this is the first case report in Korea.

Keywords

References

  1. Baird K. Lymphoplasmacytic gingivitis in a cat. Can Vet J 2005; 46: 530-532.
  2. Dowers K, Hawley JR, Brewer MM, Morris AK, Radecki V, Lappin MR. Association of Bartonella species, feline calicivirus and feline herpesvirus 1 infection with givostomatitis in cats. J Feline Med Surg 2010; 12: 314-321. https://doi.org/10.1016/j.jfms.2009.10.007
  3. Herring IP, Troy GC, Toth TE, Champagne ES, Pickett JP, Haines DM. Feline leukemia virus detection in corneal tissues of cats by polymerase chain reaction and immunohistochemistry. Vet Ophthalmol 2001; 4: 119-126. https://doi.org/10.1046/j.1463-5224.2001.00187.x
  4. Lommer MJ, Verstraete FJM. Concurrent oral shedding of feline calicivirus and feline herpesvirus 1 in cats with chronic gingivostomatitis. Oral Microbiol Immunol 2003; 18: 131-134. https://doi.org/10.1034/j.1399-302X.2003.00033.x
  5. McGavin MD, Zachary JF. Alimentary system. In: Pathologic basis of veterinary disease. 4th ed. St. Louis: Mosby Elsevier. 2007: 308-310.
  6. Meuten DJ. Tumors of the alimentary tract. In: Tumors in Domestic Animals. 4th ed. Ames: Iowa State Press. 2002: 401-409.
  7. Niemiec BA. Oral pathology. Top Companion Anim Med 2008; 23: 59-71. https://doi.org/10.1053/j.tcam.2008.02.002
  8. Quimby JM, Elston T, Hawley J, Brewer M, Miller A, Lappin MR. Evaluation of the association of Bartonella species, feline herpesvirus 1, feline calicivirus, feline leukemia virus and feline immunodeficiency virus with chronic feline gingivostomatitis. J Feline Med Surg 2008; 10: 66-72. https://doi.org/10.1016/j.jfms.2007.05.007
  9. Sykes JE, Studdert, Browning GF. Detection and strain differentiation of feline calicivirus in conjunctival swabs by RTPCR of the hypervariable region of the capsid protein gene. Arch Virol 1998; 143: 1321-1334. https://doi.org/10.1007/s007050050378
  10. Suchy A, Bauder B, Gelbmann W, Lohr CV, Teifke JP, Weissenbock H. Diagnosis of feline herpesvirus infection by immunohistochemistry, polymerase chain reaction, and in situ hybridization. J Vet Diagn Invest 2000; 12: 186-191. https://doi.org/10.1177/104063870001200220
  11. Tenorio AP, Franti CE, Madewell BR, Pedersen NC. Chronic oral infections of cats and their relationship to persistent oral carriage of feline calici-, immunodeficiency, or leukemia viruses. Vet Immunol Immunopathol 1991; 29: 1-14. https://doi.org/10.1016/0165-2427(91)90048-H
  12. Tutt C, Deeprose J, Crossley D. Feline inflammatory, infectious and other oral conditions. In: BSAVA Manual of Canine and Feline Dentistry, 3rd ed. Glouchester: BSAVA. 2007: 126-147.
  13. Vahlenkamp TW, Egberink HF, van Eijk MJT, Slotboom- Kamphorst AME, Verschoor EJ, Horzinek MC, de Ronde A. Competitive reverse transcription-polymerase chain reaction for quantitation of feline immunodeficiency virus. J Virol Methods 1995; 52: 335-346. https://doi.org/10.1016/0166-0934(94)00169-H