한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제28권1호
  • /
  • Pages.154-158
  • /
  • 2011
  • /
  • 1598-298X(pISSN)
  • /
  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

시츄견에서 경부 림프절로 전이된 편도 편평세포암종

Cervical Lymph Node Metastases of Tonsillar Squamous Cell Carcinoma in a Shih-tzu

  • Jung, Dong-In (Research Institute of Life Sciences, Gyeongsang National University) ;
  • Lee, Kyung-Woo (Research Institute of Life Sciences, Gyeongsang National University) ;
  • Park, Ki-Tae (Research Institute of Life Sciences, Gyeongsang National University) ;
  • Wang, Ji-Hwan (Research Institute of Life Sciences, Gyeongsang National University) ;
  • Yeon, Seong-Chan (Research Institute of Life Sciences, Gyeongsang National University) ;
  • Lee, Hyo-Jong (Research Institute of Life Sciences, Gyeongsang National University) ;
  • Lee, Hee-Chun (Research Institute of Life Sciences, Gyeongsang National University)
  • 심사 : 2011.01.24
  • 발행 : 2011.02.28
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

A 8-year-old female Shih-tzu dog (weighting 4.5 kg) with history of both hindlimb lameness and cervical mass was presented to Veterinary Teaching Hospital, Gyeongsang National University. In physical examination, ataxia, kyphosis, back pain and cervical mass were identified. Marked periosteal new bone formation of the fourth lumbar vertebra and soft tissue opacity mass of cervical region were observed in survey radiographs. Transverse computed tomography (CT) scan obtained at the lumbar and cervical lesions shown a well defined multilobulated bony mass and partially destructive lytic lesions the fourth lumbar vertebral body and a enlarged retropharyngeal lymph node with heterogeneous contrast enhancement and moderately enhancing left tonsillar mass. Neoplastic squamous epithelium which have developed vessel and lymphocyte infiltration in surrounding tissue were confirmed based on histopathologic examination. Based on the diagnostic findings the dog was diagnosed as a cervical lymph node metastases of tonsillar squamous cell carcinoma.

키워드

참고문헌

  1. Bertone ER, Snyder LA, Moore AS. Enviromental and lifestyle risk factors for oral squamous cell carcinoma in domestic cats. J Vet Intern Med 2003; 17: 557-562 https://doi.org/10.1111/j.1939-1676.2003.tb02478.x
  2. Brooks MB, Matus RE, Leifer CE, Alfieri AA, Patnaik AK. Chemotherapy versus chemotherapy plus radiotherapy in the treatment of tonsillar squamous cell carcinoma in the dog. J Vet Intern Med 1988; 2: 206-211. https://doi.org/10.1111/j.1939-1676.1988.tb00318.x
  3. Cianchetti M, Mancuso AA, Amdur RJ, Werning JW, Kirwan J, Morris CG, Mendenhall WM. Diagnostic evaluation of squamous cell carcinoma metastatic to cervical lymph nodes from an unknown head and neck primary site. Laryngoscope 2009; 119: 2348-2354. https://doi.org/10.1002/lary.20638
  4. Da Mosto MC, Zanetti F, Boscolo-Rizzo P. Pattern of lymph node metastases in squamous cell carcinoma of the tonsil: implication for selective neck dissection. Oral Oncol 2009; 45: 212-217. https://doi.org/10.1016/j.oraloncology.2008.05.004
  5. de Bree R, Deurloo EE, Snow GB, Leemans CR. Screening for distant metastases in patients with head and neck cancer. Laryngoscope 2000; 110: 397-401. https://doi.org/10.1097/00005537-200003000-00012
  6. de Vos JP, Burm AG, Focker AP, Boschloo H, Karsijns M, van der Waal I. Piroxicam and carboplatin as a combination treatment of canine oral non-tonsillar squamous cell carcinoma: a pilot study and a literature review of a canine model of human head and neck squamous cell carcinoma. Vet Comp Oncol 2005; 3: 16-24. https://doi.org/10.1111/j.1476-5810.2005.00065.x
  7. Murphy S, Hayes A, Adams V, Maglennon G, Neath P, Ladlow J, Brearley MJ. Role of carboplatin in multi-modality treatment of canine tonsillar squamous cell carcinoma-a case series of five dogs. J Small Anim Pract 2006; 47: 216-220. https://doi.org/10.1111/j.1748-5827.2006.00020.x
  8. Spector JG, Sessions DG, Haughey BH, Chao KS, Simpson J, El Mofty S, Perez CA. Delayed regional metastases, distant metastases, and second primary malignancies in squamous cell carcinomas of the larynx and hypopharynx. Laryngoscope 2001; 111: 1079-1087. https://doi.org/10.1097/00005537-200106000-00028
  9. Stambuk HE, Karimi S, Lee N, Patel SG. Oral cavity and oropharynx tumors. Radiol Clin North Am 2007; 45: 1-20. https://doi.org/10.1016/j.rcl.2006.10.010
  10. Webb JL, Burns RE, Brown HM, Leroy BE, Kosarek CE. Squamous cell carcinoma. Compend Contin Educ Vet 2009; 31: 133-142.
  11. White RAS, Jefferies AR, Freedman LS. Clinical staging for oropharyngeal malignancies in the dog. J Small Anim Pract 1985; 26: 581-594. https://doi.org/10.1111/j.1748-5827.1985.tb02184.x