Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Synthesis and Modification of Novel Iminecalix[4]arene Derivatives

  • Nimse, Satish Balasaheb (Institute for Applied Chemistry and Department of Chemistry, Hallym University) ;
  • Kim, Jun-Bae (Institute for Applied Chemistry and Department of Chemistry, Hallym University) ;
  • Lee, Jeong-Tae (Institute for Applied Chemistry and Department of Chemistry, Hallym University) ;
  • Song, Keum-Soo (Biometrix Technology, Inc.) ;
  • Kim, Jung-Hoon (Biometrix Technology, Inc.) ;
  • Ta, Van-Thao (Institute for Applied Chemistry and Department of Chemistry, Hallym University) ;
  • Nguyen, Van-Thuan (Institute for Applied Chemistry and Department of Chemistry, Hallym University) ;
  • Kim, Tai-Sun (Institute for Applied Chemistry and Department of Chemistry, Hallym University)
  • Received : 2010.10.19
  • Accepted : 2011.01.27
  • Published : 2011.04.20
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Abstract

The synthesis of novel iminecalix[4]arenes and further modification thereafter is described using a synthetic strategy. The reaction of the benzaldehyde derivatives with tetraamine functions on the calix[4]arene easily afforded the pure compounds in 92.4-95.7% yields, regardless of the effect of the substituents on the benzaldehyde derivatives. These compounds were stable under the conditions to obtain their analogue dialkylated in the narrow rim, with 83.2-89.9% yields. Characterization of the newly synthesized iminecalix[4]arene derivatives by spectroscopic methods revealed that all compounds are in the cone conformations.

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