Journal of Mushroom (한국버섯학회지)

The Korean Society of Mushroom Science (한국버섯학회)
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Anti-inflammatory effects of mushroom extracts in Korea

국내 자생버섯 추출물의 항염활성

  • Noh, Hyung-Jun (National Institute of Horticultural & Herbal Science, Rural Development Administration) ;
  • Choi, Su-Im (YD life science, Seoul science technology university) ;
  • Lee, Kang-Hyo (National Institute of Horticultural & Herbal Science, Rural Development Administration) ;
  • Jang, Kab-Yeul (National Institute of Horticultural & Herbal Science, Rural Development Administration) ;
  • Cho, Jae-Han (National Institute of Horticultural & Herbal Science, Rural Development Administration) ;
  • Sung, Gi-Ho (National Institute of Horticultural & Herbal Science, Rural Development Administration) ;
  • Kim, Geum-Soog (National Institute of Horticultural & Herbal Science, Rural Development Administration) ;
  • Lee, Seung-Eun (National Institute of Horticultural & Herbal Science, Rural Development Administration) ;
  • Kim, Seung-Yu (National Institute of Horticultural & Herbal Science, Rural Development Administration)
  • 노형준 (농촌진흥청 국립원예특작과학원) ;
  • 최수임 (와이디생명과학) ;
  • 이강효 (농촌진흥청 국립원예특작과학원) ;
  • 장갑열 (농촌진흥청 국립원예특작과학원) ;
  • 조재한 (농촌진흥청 국립원예특작과학원) ;
  • 성기호 (농촌진흥청 국립원예특작과학원) ;
  • 김금숙 (농촌진흥청 국립원예특작과학원) ;
  • 이승은 (농촌진흥청 국립원예특작과학원) ;
  • 김승유 (농촌진흥청 국립원예특작과학원)
  • Received : 2011.06.03
  • Accepted : 2011.06.12
  • Published : 2011.06.30
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Abstract

This study was carried out to investigate anti-inflammatory effects of collected mushroom in Korea. Anti-inflammatory effects analysis was followed by MTT test and nitric oxide inhibition activity. Thirty mushrooms were screened and twelve mushrooms were selected about MTT assay and three mushrooms were good at nitric oxide inhibition test. In our result, three mushrooms: Amanita virgineoides, Tylopilus neofelleus, Armillaria tabescens were good resource for anti-inflammatory effects and to be followed more research about relat.

국내자생 야생버섯의 항염증 활성검증을 위해 7월~8월에 채집된 버섯을 메탄올 추출하여 DMSO의 희석한 후 Nitric oxide 저해능을 분석하였다. 30여종의 버섯 추출물을 세포활력도를 측정하기 위해 MTT 분석결과 12개의 버섯추출물이 비교적 안정된 세포활력도를 보였으며, nitric oxide 저해능을 양성대조군(LPS)와 비교한 결과 Amanita virgineoides:흰가시광대버섯, Tylopilus neofelleus:제주쓴맛그물버섯, Armillariella tabescens:뽕나무버섯붙이, Amanita abrupta:양파광대버섯, Agaricus subrutilescens:진갈색주름버섯, Boletus subvelutips 7종의 버섯은 18%이상의 우수한 nitric oxide저해능을 보였다.

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