Korean Journal of Clinical Pharmacy (한국임상약학회지)

Korean College Of Clinical Pharmacy (한국임상약학회)
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The Effect of Helicobacter pylori eradication in Patients with H. pylori(+) Idiopathic thrombocytopenic Purpura : Case study

위나선균양성 특발성혈소판감소성자반증에서 위나선균박멸요법의 효과: 증례 연구

  • Park, Chi-Young (Department of Internal Medicine, Chosun University Hospital) ;
  • Moon, Hong-Seop (Department of Pharmacy, Chosun University Hospital)
  • 박치영 (조선대학교 병원 내과) ;
  • 문홍섭 (조선대학교 병원 약제부)
  • Received : 2010.12.13
  • Accepted : 2011.02.17
  • Published : 2011.03.31
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Abstract

Idiopathic thrombocytopenic purpura is a potentially life-threatening condition characterised by thrombocytopenia and mediated by an autoimmune mechanism. Several recent studies have suggested that an association exists between H. pylori eradication and improvement in platelet count in a significant proportion of patients with idiopathic thrombocytopenic purpura. This study confirmed the efficacy of H. pylori eradication in increasing the platelet count in steroid refractory idiopathic thrombocytopenic purpura patients. Eradication therapy is simple and inexpensive, with limited toxicity and the advantage of avoiding long-term immunosuppressive treatment.

Keywords

References

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