A Case of Prolonged Coagulopathy in a Patient Intoxicated with Superwarfarin Rodenticide

슈퍼와파린(superwarfarin) 살서제 중독으로 인한 장기간 혈액응고장애 1례

  • Park, Chan-Woo (Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University) ;
  • Cho, Jun-Hwi (Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University) ;
  • Bae, Joon-Ho (Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University) ;
  • Moon, Joong-Bum (Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University) ;
  • Chon, Sung-Bin (Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University) ;
  • Ahn, Ki-Ohk (Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University) ;
  • Lee, Hui-Young (Department of Internal Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University)
  • 박찬우 (강원대학교 의학전문대학원 응급의학교실) ;
  • 조준휘 (강원대학교 의학전문대학원 응급의학교실) ;
  • 배준호 (강원대학교 의학전문대학원 응급의학교실) ;
  • 문중범 (강원대학교 의학전문대학원 응급의학교실) ;
  • 천성빈 (강원대학교 의학전문대학원 응급의학교실) ;
  • 안기옥 (강원대학교 의학전문대학원 응급의학교실) ;
  • 이희영 (강원대학교 의학전문대학원 내과학교실)
  • Received : 2011.06.15
  • Accepted : 2011.07.14
  • Published : 2011.12.31

Abstract

Superwarfarin, such as brodifacoum, is a highly lethal vitamin K antagonist used as a rodenticide. Brodifacoum has a particularly long half-life in the body, which ranges to several months, and therefore requires prolonged treatment with antidotal vitamin K. We experienced a case whereby an 18-year-old male was presented to the hospital with a severe bleeding disorder. It was discovered that he had ingested brodifacoum rodenticide with intent to commit suicide. Despite continual treatment with vitamin K, the bleeding disorder persisted for several months before he recovered. We report this case with literature review.

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