Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Factors Associated with Delayed Neuropsychological Sequelae in Acute Carbon Monoxide Poisoning Patients Treated by Hyperbaric Oxygen

고압산소치료를 받은 급성 일산화탄소 중독 환자들에서 발생한 지연성 신경정신과학적 후유증 발생과 관계된 인자

  • Lee, Dong-Ha (Department of Emergency Medicine, School of Medicine, Keimyung University, Dongsan Medical Center) ;
  • Choi, Woo-Ik (Department of Emergency Medicine, School of Medicine, Keimyung University, Dongsan Medical Center)
  • 이동하 (계명대학교 의과대학 동산의료원 응급의학과) ;
  • 최우익 (계명대학교 의과대학 동산의료원 응급의학과)
  • Received : 2011.07.21
  • Accepted : 2011.10.06
  • Published : 2011.12.31
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Abstract

Purpose: Delayed neuropsychological sequelae (DNS) commonly occurs after recovery from acute carbon monoxide poisoning. The aim of this article is to identify the factors associated with DNS development. Methods: We retrospectively evaluated patients, admitted to the medical center emergency department from June 2005 to March 2011, who were suffering from acute carbon monoxide (CO) poisoning. We categorized the patients into two groups - those with DNS, and those without DNS. Multiple regression analysis was performed to identify the factors related to manifestation of DNS. Results: Of the total one hundred fifty seven patients (157) recruited for the study, twenty two (22) developed DNS. Longer CO exposure times and lower GCS scores were positively associated with development of DNS symptoms. Conclusion: Our study identified two potential factors which are predictive of DNS development in CO intoxication, however, more studies are needed. Adequate follow-up after hospital discharge to monitor for and accurately identify manifestation of DNS, is also important.

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