참고문헌
- Au HC, Seo BB, Matsuno-Yagi A, Yagi T, Scheffler IE (1999): The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria. Proc Natl Acad Sci USA 96:4354-4359. https://doi.org/10.1073/pnas.96.8.4354
- Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, Greenamyre JT (2000): Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 3:1301-1306. https://doi.org/10.1038/81834
- Buchanan SK, Walker JE (1996): Large-scale chromatographic purification of F1F0-ATPase and complex I from bovine heart mitochondria. Biochem J 318:343- 349. https://doi.org/10.1042/bj3180343
- Burger C, Nash K, Mandel RJ (2005): Recombinant adeno-associated viral vectors in the nervous system. Hum Gene Ther 16(7):781-91. https://doi.org/10.1089/hum.2005.16.781
- Chomyn A, Mariottini P, Cleeter MWJ, Ragan CI, Matsuno- Yagi A, Hatefi Y, Doolittle RF, Attardi G (1985): Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase. Nature 314:591-597.
- Chomyn A, Cleeter MWJ, Ragan CI, Riley M, Doolittle RF, Attardi G (1986): URF6, last unidentified reading frame of human mtDNA, codes for an NADH dehydrogenase subunit. Science 234:614-618. https://doi.org/10.1126/science.3764430
- Dawson TM, Dawson VL (2003): Molecular pathways of neurodegeneration in Parkinson's disease. Science 302:819-822. https://doi.org/10.1126/science.1087753
- De Francesco L, Scheffler IE, Bissell M (1976): A respiration- deficient Chinese hamster cell line with a defect in NADH-coenzyme Q reductase. J Biol Chem 251: 4588-4595.
- de Vries S, Grivell LA (1988): Purification and characterization of a rotenone-insensitive NADH-Q6 oxidoreductase from mitochondria of Saccharomyces cerevisiae. Eur J Biochem 176:377-384. https://doi.org/10.1111/j.1432-1033.1988.tb14292.x
- de Vries S, Van Witzenburg R, Grivell LA, Marres CAM (1992): Primary structure and import pathway of the rotenone-insensitive NADH-ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae. Eur J Biochem 203:587-592. https://doi.org/10.1111/j.1432-1033.1992.tb16587.x
- Flotte TR, Afione SA, Conrad C, McGrath SA, Solow R, Oka H, Zeitlin PL, Guggino WB, Carter BJ (1993): Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector. Proc Natl Acad Sci USA 90:10613-10617. https://doi.org/10.1073/pnas.90.22.10613
- Granger DL, Lehninger AL (1982): Sites of inhibition of mitochondrial electron transport in macrophage- injured neoplastic cells. J Cell Biol 95: 527- 535. https://doi.org/10.1083/jcb.95.2.527
- Guy J, Qi X, Pallotti F, Schon EA, Manfredi G, Carelli V, Martinuzzi A, Hauswirth WW, Lewin AS (2002): Rescue of a mitochondrial deficiency causing Leber hereditary optic neuropathy. Ann Neurol 52: 534-542. https://doi.org/10.1002/ana.10354
- Hatefi Y (1985): The mitochondrial electron transport and oxidative phosphorylation system. Annu Rev Biochem 54:1015-1069. https://doi.org/10.1146/annurev.bi.54.070185.005055
- Hofhaus G, Shakeley RM, Attardi G (1996): Use of polarography to detect respiration defects in cell cultures. Methods Enzymol 264:476-483.
- Kitajima-Ihara T, Yagi T (1998): Rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria: the enzyme expressed in Escherichia coli acts as a member of the respiratory chain in the host cells. FEBS Lett 421:37-40. https://doi.org/10.1016/S0014-5793(97)01533-0
- Klimatcheva E, Rosenblatt JD, Planelles V (1999): Lentiviral vectors and gene therapy. Front Biosci 4:D- 481-D496. https://doi.org/10.2741/Klimatcheva
- Laemmli UK (1970): Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685. https://doi.org/10.1038/227680a0
- Luft R (1994): The development of mitochondrial medicine. Proc Natl Acad Sci USA 91(19):8731-8. https://doi.org/10.1073/pnas.91.19.8731
- Manfredi G, Fu J, Ojaimi J, Sadlock JE, Kwong JQ, Guy J, Schon EA (2002): Rescue of a deficiency in ATP synthesis by transfer of MTATP6, a mitochondrial DNA-encoded gene, to the nucleus. Nat Genet 30:394-399. https://doi.org/10.1038/ng851
-
Manning-Bog AB, McCormack AL, Li J, Uversky VN, Fink AL, Di Monte DA (2002): The herbicide paraquat causes up-regulation and aggregation of
$\alpha$ -synuclein in mice: paraquat and$\alpha$ -synuclein. J Biol Chem 277:1641-1644. https://doi.org/10.1074/jbc.C100560200 - Marres CAM, de Vries S, Grivell LA (1991): Isolation and inactivation of the nuclear gene encoding the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyce cerevisiae. Eur J Biochem 195:857-862. https://doi.org/10.1111/j.1432-1033.1991.tb15775.x
- Marella M, Seo BB, Flotte TR, Matsuno-Yagi A, Yagi T (2011): No immune responses by the expression of the yeast ndi1 protein in rats. PLoS One 6(10):e25910 https://doi.org/10.1371/journal.pone.0025910
- Muzyczka N (1994): Adeno-associated virus (AAV) vectors: will they work? J Clin Invest 94:1351. https://doi.org/10.1172/JCI117468
- Naldini L, Blomer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D (1996): In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272:263-267. https://doi.org/10.1126/science.272.5259.263
- Nesnow S, Grindstaff RD, Lambert G, Padgett WT, Bruno M, Ge Y, Chen PJ, Wood CE, Murphy L (2011): Propiconazole increases reactive oxygen species levels in mouse hepatic cells in culture and in mouse liver by a cytochrome P450 enzyme mediated process. Chem Biol Interact 194 (1):79-89. https://doi.org/10.1016/j.cbi.2011.08.002
- Robbins PD, Ghivizzani SC (1998): Viral vectors for gene therapy. Pharmacol Ther 80:35-47. https://doi.org/10.1016/S0163-7258(98)00020-5
- Sherer TB, Betarbet R, Greenamyre JT (2002): Environment, mitochondria, and Parkinson's disease. Neuroscientist 8:192-197.
- Sherer TB, Betarbet R, Testa CM, Seo BB, Richardson JR, Kim JH, Miller GW, Yagi T, Matsuno-Yagi A, Greenamyre JT (2003): Mechanism of toxicity in rotenone models of Parkinson's disease. J Neurosci 23:10756-10764.
- Shoffner JM, Wallace DC (1994): Oxidative phosphorylation diseases and mitochondrial DNA mutations diagnosis and treatment. Rev Nutr 14:535-568. https://doi.org/10.1146/annurev.nu.14.070194.002535
- Seo BB, Kitajima-Ihara T, Chan EK, Scheffler IE, Matsuno- Yagi A, Yagi T (1998): Molecular remedy of complex I defects: Rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells. Proc Natl Acad Sci USA 95:9167-9171. https://doi.org/10.1073/pnas.95.16.9167
- Seo BB, Matsuno-Yagi A, Yagi T (1999): Modulation of oxidative phosphorylation of human kidney 293 cells by transfection with the internal rotenone-insensitive NADH-quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae. Biochim Biophys Acta 1412:56-65. https://doi.org/10.1016/S0005-2728(99)00051-1
- Seo BB, Wang J, Flotte TR, Yagi T, Matsuno-Yagi A (2000): Use of the NADH-quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae as a possible cure for complex I defects in human cells. J Biol Chem 275:37774-37778. https://doi.org/10.1074/jbc.M007033200
- Singer DR, Sagnella GA, Markandu ND, Buckley MG, MacGregor GA (1987): Atrial natriuretic peptide, blood pressure, and age. Lancet 2:1394-1395.
- Todd S, Anderson C, Jolly DJ, Craik CS (2000): HIV protease as a target for retrovirus vector-mediated gene therapy. Biochim Biophys Acta 1477:168-188. https://doi.org/10.1016/S0167-4838(99)00272-1
- Trounce IA, Kim YL, Jun AS, Wallace DC (1996): Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines. Method Enzymol 264: 484-509.
- Wallace DC (1992): Diseases of the mitochondrial DNA. Annu Rev Biochem 61:1175-1212. https://doi.org/10.1146/annurev.bi.61.070192.005523
- Wallace DC, Shoffner JM, Watts RL, Juncos JL, Torroni A (1992): Mitochondrial oxidative phosphorylation defects in Parkinson's disease. Ann Neurol 32: 113-114. https://doi.org/10.1002/ana.410320123
- Wallace DC (1993): Mitochondrial diseases: genotype versus phenotype. Trends Genet 9(4):128-33. https://doi.org/10.1016/0168-9525(93)90207-X
- Wu N, Ataai MM (2000): Production of viral vectors for gene therapy applications. Curr Opin Biotechnol 11:205-208. https://doi.org/10.1016/S0958-1669(00)00080-X
- Yagi T (1993): The bacterial energy-transducing NADH- quinone oxidoreductases. Biochim Biophys Acta 1141:1-17. https://doi.org/10.1016/0005-2728(93)90182-F