Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Dermal and Ocular Irritation Studies of Honeybee (Apis mellifera L.) venom

봉독의 피부자극시험 및 안점막자극시험

  • Han, Sang-Mi (National Academy of Agricultural Science, Rural Development Administration) ;
  • Lee, Kwang-Gil (National Academy of Agricultural Science, Rural Development Administration) ;
  • Yeo, Joo-Hong (National Academy of Agricultural Science, Rural Development Administration)
  • 한상미 (농촌진흥청 국립농업과학원) ;
  • 이광길 (농촌진흥청 국립농업과학원) ;
  • 여주홍 (농촌진흥청 국립농업과학원)
  • Received : 2011.01.27
  • Accepted : 2011.03.15
  • Published : 2011.03.31
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Abstract

The study of irritation and toxicity of honeybee(Apis mellifera. L) venom collected by a bee venom collector applied topically to the skin and mucous membrane were carried out to prove the safety of honeybee venom in clinical use. Animal for the research was the rabbit and the solution for the test was made from honeybee venom. Six animals were used for the skin test and nine animals were used for the eye mucous membrane test. In results, both tests proved that honeybee venom makes no irritable reaction on skin and eye mucous membrane of rabbit. We consider that this result is helpful for saying about the safety of honeybee venom in clinical use.

Keywords

References

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