Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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The Extract of Aster glehni Leaves Rich in Caffeoylquinic Acids Prevents Atherogenic Index, Oxidative Stress, and Body Weight Increase in High-Fat Diet-induced Rats

고지방 식이 흰쥐에서 섬쑥부쟁이 Caffeoylquinic Acid 고함유 추출물의 동맥경화 위험지수, 산화적 스트레스 및 체중에 대한 효과

  • Kim, Myung-Hoe (Department of Pharmaceutical Engineering, Sangji University) ;
  • Nugroho, Agung (Department of Agro-industrial Technology, Lambung Mangkurat University) ;
  • Choi, Jong-Won (College of Pharmacy, Kyungsung University) ;
  • Park, Hee-Juhn (Department of Pharmaceutical Engineering, Sangji University)
  • Received : 2011.01.08
  • Accepted : 2011.02.24
  • Published : 2011.03.31
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Abstract

In an attempt to find the activity of Aster glehni (Compositae) leaves on the obesity in vivo, 30% ethanolic extract rich in caffeoylquinic acids was orally treated with 100 and 200 mg/kg for consecutive four weeks during feeding high-fat diet in rats for 6 weeks. This extract prevented the increase of atherogenic index and body weight and oxidative stress from dietinduced obese rats probably due to the pharmacological mechanism of the CQ complex.

Keywords

References

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