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Pyrogallin, an ATP-Competitive Inhibitor of JAK3

  • Lee, Byung-Il (Cancer Cell and Molecular Biology Branch, Division of Cancer Biology, Research Institute, National Cancer Center) ;
  • Ahn, Hyung-Jun (Life Sciences Research Division, Korea Institute of Science and Technology) ;
  • Han, Ki-Cheol (Life Sciences Research Division, Korea Institute of Science and Technology) ;
  • Ahn, Dae-Ro (Life Sciences Research Division, Korea Institute of Science and Technology) ;
  • Shin, Dong-Yun (College of Pharmacy, Gachon University of Medicine and Science)
  • Received : 2010.07.13
  • Accepted : 2010.10.25
  • Published : 2011.03.20

Abstract

Keywords

References

  1. Aaronson, D. S.; Horvath, C.M. Science 2002, 296, 1653-1655. https://doi.org/10.1126/science.1071545
  2. O’Shea, J. J.; Pesu,M.; Borie, D. C.; Changelianl, P. S. Nat. Rev.Drug. Disc. 2004, 3, 555-564. https://doi.org/10.1038/nrd1441
  3. Chen, Z.; Lund, R.; Aittokallio, T.; Kosonen,M.; Nevalainen, O.;Lahesmaa, R. J. Immunol. 2003, 171, 3627-3635. https://doi.org/10.4049/jimmunol.171.7.3627
  4. Leonard,W. J.; O’Shea, J. J. Ann. Rev. Immunol. 1998, 16, 293-322. https://doi.org/10.1146/annurev.immunol.16.1.293
  5. West, K. Curr. Opin. Investig. Drugs 2009, 10, 491-504.
  6. Changelian, P. S.; Flanagan,M. E.; Ball, D. J.; Kent, C. R.;Magnuson,K. S.; Martin, W. H., et al. Science 2003, 302, 875-878. https://doi.org/10.1126/science.1087061
  7. Jiang, J.-K.; Ghoreschi, K.; Deflorian, F.; Chen, Z.; Perreira, M.;Pesu,M.; Smith, J.; Nguyen, D.; Liu, E. H.; Leister, W.; Costanzi,S.; O’Shea, J. J.; Thomas, C. J. J. Med. Chem. 2008, 51, 8012-8018. https://doi.org/10.1021/jm801142b
  8. Boggon, T. J.; Li, Y.;Manley, P.W.; Eck,M. J. Blood 2005, 106,996-1002. https://doi.org/10.1182/blood-2005-02-0707
  9. Chong, C. R.; Sullivan, D. J. Nature 2007, 448, 645-646. https://doi.org/10.1038/448645a
  10. Takino, Y.; Imagawa, H. Agr. Biol. Chem. 1964, 28, 125-130. https://doi.org/10.1271/bbb1961.28.125
  11. Abou-Karam, M.; Shier,W. T. Phytother. Res. 1999, 13, 337-340. https://doi.org/10.1002/(SICI)1099-1573(199906)13:4<337::AID-PTR451>3.0.CO;2-J
  12. Zhang, X.; Gureasko, J.; Shen, K.; Cole, P. A.; Kuriyan, J. Cell2006, 125, 1137-1149. https://doi.org/10.1016/j.cell.2006.05.013
  13. Yang, S.-M.;Malaviya, R.;Wilson, L. J.; Argentieri, R.; Chen, X.;Yang, C.; Wang, B.; Cavender, D.; Murray, W. V. Bioorg. Med.Chem. Lett. 2007, 17, 326-331. https://doi.org/10.1016/j.bmcl.2006.10.062