Usefulness of Narrow Band Imaging Endoscopy in the Diagnosis of Head and Neck Cancer : A Prospective Study

두경부암 진단의 새로운 내시경 진단방법 협대역 영상(Narrow Band Imaging, NBI)의 유용성-전향적 연구

  • Park, Jae-Hong (Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon Hospital) ;
  • Kim, Jae-Wook (Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon Hospital) ;
  • Lee, Yong-Man (Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon Hospital) ;
  • Yoo, Hye-Jin (Soonchunhyang University College of Medicine) ;
  • Tae, Kee-Yeun (Soonchunhyang University College of Medicine) ;
  • Oh, Cheon-Whan (Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon Hospital) ;
  • Chang, Hyuck-Soon (Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon Hospital) ;
  • Lee, Seung-Won (Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon Hospital)
  • 박재홍 (순천향대학교 의과대학 부천병원 이비인후-두경부외과학교실) ;
  • 김재욱 (순천향대학교 의과대학 부천병원 이비인후-두경부외과학교실) ;
  • 이용만 (순천향대학교 의과대학 부천병원 이비인후-두경부외과학교실) ;
  • 유혜진 (순천향대학교 의과대학) ;
  • 태기연 (순천향대학교 의과대학) ;
  • 오천환 (순천향대학교 의과대학 부천병원 이비인후-두경부외과학교실) ;
  • 장혁순 (순천향대학교 의과대학 부천병원 이비인후-두경부외과학교실) ;
  • 이승원 (순천향대학교 의과대학 부천병원 이비인후-두경부외과학교실)
  • Received : 2011.11.04
  • Accepted : 2011.11.15
  • Published : 2011.11.25

Abstract

Background and Objectives : Narrow Band Imaging(NBI) is a novel optical technique that enhances the visualization of superficial microvascular architecture which is commonly increased and founded as an irregular shape in a neoplastic lesion. The aim of this study is the evaluation of the usefulness of NBI in the diagnosis of Head and Neck Cancer. Subjects and Methods : From December 2009 to January 2011, 31 consecutive patients who were diagnosed with head and neck malignancy were enrolled in this prospective study. The malignant findings of NBI were demarcated brownish lesion or increased intraepithelial papillary capillary loops(IPCLs) with or without irregularity. Results : There were 29 cases(93.5%) of well demarcated brownish lesion, 26 cases(83.9%) of increased IPCLs and 4 cases(12.9%) of satellite lesions. Diagnostic accuracy of endoscopic examination was increased from 83.9% to 93.5%, when NBI was applied to the conventional endoscopy(p>0.05). Conclusion : NBI is a powerful and safe screening test, which can be performed in out patient clinic without any supplementary procedure.

Keywords

References

  1. Smith JA, Fleming WB. An approach to malignant parotid tumours. Aust NZJ Surg. 1989;59:317-320. https://doi.org/10.1111/j.1445-2197.1989.tb01573.x
  2. Wahlberg PC, Andersson KE, Biorklund AT, Moller TR. Carcinoma of the hypopharynx: Analysis of incidence and survival in Sweden over a 30-year period. Head Neck. 1998;20(8):714-719. https://doi.org/10.1002/(SICI)1097-0347(199812)20:8<714::AID-HED9>3.0.CO;2-2
  3. Johansen LV, Grau C, Overgaard J. Hypopharyngeal squamous cell carcinoma--treatment results in 138 consecutively admitted patients. Acta Oncol. 2000;39(4):529-536. https://doi.org/10.1080/028418600750013465
  4. Eckel HE, Staar S, Volling P, Sittel C, Damm M, Jungehuelsing M. Surgical treatment for hypopharynx carcinoma: Feasibility, mortality, and results. Otolaryngol Head Neck Surg. 2001;124(5): 561-569. https://doi.org/10.1067/mhn.2001.115060
  5. McGuirt WF. Panendoscopy as a screening examination for simultaneous primary tumors in head and neck cancer: A prospective sequential study and review of the literature. Laryngoscope. 1982;92(5):569-576.
  6. Morita M, Kuwano H, Ohno S, Sugimachi K, Seo Y, Tomoda H, et al. Multiple occurrence of carcinoma in the upper aerodigestive tract associated with esophageal cancer: Reference to smoking, drinking and family history. Int J Cancer. 1994;58(2): 207-210. https://doi.org/10.1002/ijc.2910580211
  7. Muto M, Hironaka S, Nakane M, Boku N, Ohtsu A, Yoshida S. Association of multiple Lugol-voiding lesions with synchronous and metachronous esophageal squamous cell carcinoma in patients with head and neck cancer. Gastrointest Endosc. 2002;56 (4):517-521. https://doi.org/10.1016/S0016-5107(02)70436-7
  8. Inoue H, Yokoyama A, Kudo SE. [Ultrahigh magnifying endoscopy: Development of CM double staining for endocytoscopy and its safety]. Nippon Rinsho. 2010;68(7):1247-1252.
  9. Muto M, Horimatsu T, Ezoe Y, Hori K, Yukawa Y, Morita S, et al. Narrow-band imaging of the gastrointestinal tract. J Gastro enterol. 2009;44(1):13-25. https://doi.org/10.1007/s00535-008-2291-5
  10. Mori M, Adachi Y, Matsushima T, Matsuda H, Kuwano H, Sugimachi K. Lugol staining pattern and histology of esophageal lesions. Am J Gastroenterol. 1993;88(5):701-705.
  11. Inoue H, Rey JF, Lightdale C. Lugol chromoendoscopy for eso-phageal squamous cell cancer. Endoscopy. 2001;33(1):75-79.
  12. Uedo N, Iishi H, Tatsuta M, Yamada T, Ogiyama H, Imanaka K, et al. A novel videoendoscopy system by using autofluorescence and reflectance imaging for diagnosis of esophagogastric cancers. Gastrointest Endosc. 2005;62(4):521-528. https://doi.org/10.1016/j.gie.2005.06.031
  13. Kara MA, Peters FP, Fockens P, ten Kate FJ, Bergman JJ. Endoscopic video-autofluorescence imaging followed by narrow band imaging for detecting early neoplasia in Barrett's esophagus. Gastrointest Endosc. 2006;64(2):176-185. https://doi.org/10.1016/j.gie.2005.11.050
  14. Curvers WL, Singh R, Song LM, Wolfsen HC, Ragunath K, Wang K, et al. Endoscopic tri-modal imaging for detection of early neoplasia in Barrett's oesophagus: a multi-centre feasibility study using high-resolution endoscopy, autofluorescence imaging and narrow band imaging incorporated in one endoscopy system. Gut. 2008;57(2):167-172. https://doi.org/10.1136/gut.2007.134213
  15. Yoshida Y, Goda K, Tajiri H, Urashima M, Yoshimura N, Kato T. Assessment of novel endoscopic techniques for visualizing superficial esophageal squamous cell carcinoma: Autofluorescence and narrow-band imaging. Dis Esophagus. 2009;22(5): 439-446. https://doi.org/10.1111/j.1442-2050.2008.00925.x
  16. Inoue H. [Endoscopic diagnosis of tissue atypism(EA) in the pharyngeal and esophageal squamous epithelium; IPCL pattern classification and ECA classification]. Kyobu Geka. 2007; 60(8 Suppl):768-775.
  17. Kumagai Y, Inoue H, Nagai K, Kawano T, Iwai T. Magnifying endoscopy, stereoscopic microscopy, and the microvascular architecture of superficial esophageal carcinoma. Endoscopy. 2002;34(5):369-375. https://doi.org/10.1055/s-2002-25285
  18. Muto M, Nakane M, Katada C, Sano Y, Ohtsu A, Esumi H, et al. Squamous cell carcinoma in situ at oropharyngeal and hypopharyngeal mucosal sites. Cancer. 2004;101(6):1375-1381. https://doi.org/10.1002/cncr.20482
  19. Piazza C, Cocco D, De Benedetto L, Bon FD, Nicolai P, Peretti G. Role of narrow-band imaging and high-definition television in the surveillance of head and neck squamous cell cancer after chemo- and/or radiotherapy. Eur Arch Otorhinolaryngol. 2010; 267(9):1423-1428. https://doi.org/10.1007/s00405-010-1236-9
  20. Watanabe A, Taniguchi M, Tsujie H, Hosokawa M, Fujita M, Sasaki S. The value of narrow band imaging for early detection of laryngeal cancer. Eur Arch Otorhinolaryngol. 2009;266(7): 1017-1023. https://doi.org/10.1007/s00405-008-0835-1