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A Case of Metastatic Low-grade Endometrial Stromal Sarcoma Patient Managed with Allergen-removed Rhus Verniciflua Stokes Based on Traditional Korean Medicine

알러젠 제거 옻나무 추출물 위주의 한방치료로 관리한 저등급 자궁내막 간질육종 증례 보고

  • Kwon, Eun-Mi (Korean Traditional Medicine Cancer Center, Kyung Hee University Hospital at Gangdong) ;
  • Lee, Soo-Kyung (Korean Traditional Medicine Cancer Center, Kyung Hee University Hospital at Gangdong) ;
  • Lee, Sang-Hun (Korean Traditional Medicine Cancer Center, Kyung Hee University Hospital at Gangdong) ;
  • Kim, Kyung-Suk (Korean Traditional Medicine Cancer Center, Kyung Hee University Hospital at Gangdong) ;
  • Yoon, Seong-Woo (Korean Traditional Medicine Cancer Center, Kyung Hee University Hospital at Gangdong) ;
  • Choi, Won-Cheol (Korean Traditional Medicine Cancer Center, Kyung Hee University Hospital at Gangdong) ;
  • Han, Jong-Hyun (Dept. of phamacology, oriental medicine of Wonkwang University) ;
  • Jung, Hyun-Sik (Korean Traditional Medicine Cancer Center, Kyung Hee University Hospital at Gangdong)
  • 권은미 (강동경희대학교병원 한방암센터) ;
  • 이수경 (강동경희대학교병원 한방암센터) ;
  • 이상헌 (강동경희대학교병원 한방암센터) ;
  • 김경석 (강동경희대학교병원 한방암센터) ;
  • 윤성우 (강동경희대학교병원 한방암센터) ;
  • 최원철 (강동경희대학교병원 한방암센터) ;
  • 한종현 (원광대학교 한의과대학 약리학교실) ;
  • 정현식 (강동경희대학교병원 한방암센터)
  • Received : 2011.10.04
  • Accepted : 2011.10.27
  • Published : 2011.12.28

Abstract

Background : Approximately 50% of patients with low-grade endometrial stromal sarcoma (LGESS) develops recurrent disease, mainly in lung or pelvis. Peritoneal metastasis of LGESS is an extremely rare phenomenon. Optimal treatment for metsatatic LGESS has not been established. Case : A 43-year-old woman had been diagnosed with LGESS with aortocaval lymphadenopathy. Despite of surgical resection, adjuvant radiation, chemotherapy and hormonal therapy, multiple lung and peritoneal metastasis developed after 15 months from initial treatment. Additional chemotherapy was done, but disease progressed. She had treatment with the allergen-removed Rhus verniciflua Stokes (aRVS) from November 2010 to May 2011. About 5 months to progression was observed. Conclusion : We suggests that aRVS could be an alternative treatment option for the metastatic LGESS patients. Further clinical studies on the efficacy of aRVS against metastatic LGESS are needed.

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