DOI QR코드

DOI QR Code

Rapid-Growing Juvenile Xanthogranuloma on the Scalp in 18-Month-Old Girl

  • Park, Young-Woo (Department of Neurosurgery, Clinical Research Institute, Chonbuk National University Medical School Hospital) ;
  • Koh, Eun-Jeong (Department of Neurosurgery, Clinical Research Institute, Chonbuk National University Medical School Hospital) ;
  • Choi, Ha-Young (Department of Neurosurgery, Clinical Research Institute, Chonbuk National University Medical School Hospital)
  • Received : 2011.03.16
  • Accepted : 2011.08.30
  • Published : 2011.09.28

Abstract

Juvenile xanthogranuloma (JXG) is an uncommon histiocytic cutaneous lesion. An 18-month-old girl visited our clinic due to rapid growing orange-yellowish lesion on scalp. Enlarging time from 1 mm to 12 mm was just 8 weeks. We excised the tumor and adjacent normal tissue. Histopathological study showed numerous eosinophils and Touton giant cells within the lesion. Immunohistochemical study revealed positive immunoreactivity for CD68 in most areas. No recurrence was seen during 12 months after resection. We report a case with rapidly growing JXG on scalp with peculiar histopathologic findings.

Keywords

References

  1. Behne K, Casey T : Ulcerated juvenile xanthogranuloma of the scalp. Australas J Dermatol 44 : 74-75, 2003 https://doi.org/10.1046/j.1440-0960.2003.00643.x
  2. Caputo R : Cutaneous nonhistiocytoses X in Freedberg IM, Eisen AZ, Wolff K, Austien KF, Goldsmith LA, Kats SI, Fitspatrick TB (eds) : Fitspatrick's Dermatology in General Medicine, ed 5. New York : McGraw Hill, 1999, Vol 2, pp1892-1902
  3. Cornips EM, Cox KE, Creytens DH, Granzen B, Weber JW, Ter Laak-Poort MP : Solitary juvenile xanthogranuloma of the temporal muscle and bone penetrating the dura mater in a 2-month-old boy. J Neurosurg Pediatrics 4 : 588-591, 2009 https://doi.org/10.3171/2009.7.PEDS09230
  4. Dehner LP : Juvenile xanthogranulomas in the first two decades of life : a clinicopathologic study of 174 cases with cutaneous andextracutaneous manifestations. Am J Surg Pathol 27 : 579-593, 2003 https://doi.org/10.1097/00000478-200305000-00003
  5. Dong H, Wang X, Liu X, Yang L, Campbell TM, Cerroni L, et al. : Rapid-growing juvenile xanthogranuloma : The reality of a second opinion teleconsultation. Letters to the editor. Australas J Dermatol 51 : 216-217, 2010 https://doi.org/10.1111/j.1440-0960.2010.00668.x
  6. Freyer DR, Kennedy R, Bostrom BC, Kohut G, Dehner LP : Juvenile xanthogranuloma : forms of systemic disease and their clinical implications. J Pediatr 129 : 227-237, 1996 https://doi.org/10.1016/S0022-3476(96)70247-0
  7. Hayashi N, Komatsu T, Komatsu T, Hiroi M, Ueno H : Juvenile xanthotreatment granuloma presenting with unilateral prominent nodule of the eyelid : report of a case and clinicopathological findings. Jpn J Ophthalmol 48 : 435-439, 2004 https://doi.org/10.1007/s10384-003-0090-3
  8. Janssen D, Harms D : Juvenile xanthogranuloma in childhood and adolescence : a clinicopathologic study of 129 patients from the kiel pediatric tumor registry. Am J Surg Pathol 29 : 21-28, 2005 https://doi.org/10.1097/01.pas.0000147395.01229.06
  9. Nakasu S, Tsuji A, Fuse I, Hirai H : Intracranial solitary juvenile xanthogranuloma successfully treated with stereotactic radiosurgery. J Neurooncol 84 : 99-102, 2007 https://doi.org/10.1007/s11060-007-9351-1
  10. Numajiri T, Nishino K, Fujiwara T, Takeda K, Sowa Y : Juvenile xanthogranuloma presenting rapid progression after curettage : a case report with clinicopathological findings. J Plast Reconstr Aesthet Surg 60 : 1248-1251, 2007 https://doi.org/10.1016/j.bjps.2006.06.010
  11. Stover DG, Alapati S, Regueria O, Turner C, Whitlock JA : Treatment of juvenile xanthogranuloma. Pediatr Blood Cancer 51 : 130-133, 2008 https://doi.org/10.1002/pbc.21523
  12. Zelger BW, Sidoroff A, Orchard G, Cerio R : Non-Langerhans cell histiocytoses. A new unifying concept. Am J Dermatopathol 18 : 490-504, 1996