A study on interaction effect among risk factors of delirium using multifactor dimensionality reduction method

  • Received : 2011.10.06
  • Accepted : 2011.11.06
  • Published : 2011.12.01

Abstract

Delirium is a neuropsychiatric disorder accompanying symptoms of hallucination, drowsiness, and tremors. It has high occurrence rates among elders, heart disease patients, and burn patients. It is a medical emergency associated with increased morbidity and mortality rates. That s why early detection and prevention of delirium ar significantly important. And This mental illness like delirium occurred by complex interaction between risk factors. In this paper, we identify risk factors and interactions between these factors for delirium using multi-factor dimensionality reduction (MDR) method.

Keywords

References

  1. Arend, E. and Christensen, M. (2009). Delirium in the intensive care unit: A review. British Association of Critical Care Nurses, Nursing in Critical Care, 14, 145-154.
  2. Brown, T. M. and Boyle, M. F. (2002). Delirium. British Medical Journal, 325, 664-647 . https://doi.org/10.1136/bmj.325.7365.664
  3. Chung, Y. J., Lee, S. Y. and Park, T. S. (2005). Multifactor dimensionality reduction in the presence of missing observations. Proceedings of the Autumn Conference, Journal of Korea Statistical Society, 31-36.
  4. Choi, Y. and Kang, K. H. (2009). On statistical methods used in medical research. Journal of the Korean Data & Information Science Society, 20, 257-367.
  5. Cole, M. and Primeau, F. (1993). Prognosis of delirium in elderly hospital patients. Canadian Medical Association Journal, 149, 41-46.
  6. Dubois, M., Skrobik, Y., Bergeron, N., Dumont, M. and Dial, S. (2001). Delirium in an intensive care unit : A study of risk factors. Intensive Care Medicine, 27, 1297-1304. https://doi.org/10.1007/s001340101017
  7. Granberg, A., Engberg, I. B. and Lundberg, D. (1996). Intensive care syndrome: A literature review. Intensive and Critical Care Nursing, 12, 173-182. https://doi.org/10.1016/S0964-3397(96)80537-4
  8. Inouye, S. (1994). The dilemma of deliriun : Clinical and research controversies regarding diagnosis and evaluation of delirium in hospitalized elderly medical patients. The American Journal of Medicine, 97, 278-288. https://doi.org/10.1016/0002-9343(94)90011-6
  9. Inouye, S., Schlesinger, M. and Lyndon, T. (1999). Delirium : A symptom of how hospital care is failing older persons and a window to improve quality of hospital care. The American Journal of Medicine, 106, 565-573. https://doi.org/10.1016/S0002-9343(99)00070-4
  10. Kang, M. W., Kim, B. Y. and Hong, J. H. (2010). Graphical regression and model assessment in logistic model. Journal of the Korean Data & Information Science Society, 21, 21-32.
  11. Kwak, K., Lee, S. B. and Do, B. S. (2011). Delirium in an emergency department : A study of risk factors. Journal of the Korean Society of Emergency Medicine, Submitted.
  12. Lee, J. H. and Lee, J. Y. (2010a). Support vector machine and multifactor dimensionality reduction for detecting major gene interactions of continuous data. Journal of the Korean Data & Information Science Society, 21, 1271-1280.
  13. Lee, J. Y. and Lee, J. H. and Lee, Y. W. (2010b). Detection of major genotypes combination by genotype matrix mapping. Journal of the Korean Data & Information Science Society, 21, 387-395.
  14. Ritchie, M. D., Hahn, L. W., Roodi, N., Bailey, L. R., Dupont, W. D., Parl F. F. and Moore, J. H. (2001). Multifactor dimensionality reduction reveals high-order interactions among estrogen- metabolism genes in sporadic breast cancer. American Journal of Human Genetics, 69, 138-147. https://doi.org/10.1086/321276
  15. Yu, M. Y., Park, J. W., Hyun, M. S. and Lee, Y. J. (2008). Factors related to delirium occurrence among the patients in the intensive care units. Journal of Korean Clinical Nursing Research, 14, 151-160.