Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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HEN Simulation of a Controlled Fluid Flow-Based Neural Cooling Probe Used for the Treatment of Focal and Spontaneous Epilepsy

  • Mohy-Ud-Din, Zia (Department of Medical & Biological Engineering, School of Medicine, Kyungpook National University) ;
  • Woo, Sang-Hyo (School of Electrical Engineering and Computer Science, Kyungpook National University) ;
  • Qun, Wei (School of Electrical Engineering and Computer Science, Kyungpook National University) ;
  • Kim, Jee-Hyum (School of Electrical Engineering and Computer Science, Kyungpook National University) ;
  • Cho, Jin-Ho (Department of Medical & Biological Engineering, School of Medicine, Kyungpook National University)
  • Received : 2010.07.07
  • Accepted : 2011.01.25
  • Published : 2011.01.31
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Abstract

Brain disorders such as epilepsy is a condition that affects an estimated 2.7 million Americans, 50,000,000 worldwide, approximately 200,000 new cases of epilepsy are diagnosed each year. Of the major chronic medical conditions, epilepsy is among the least understood. Scientists are conducting research to determine appropriate treatments, such as the use of drugs, vagus nerve stimulation, brain stimulation, and Peltier chip-based focal cooling. However, brain stimulation and Peltier chip-based stimulation processes cannot effectively stop seizures. This paper presents simulation of a novel heat enchanger network(HEN) technique designed to stop seizures by using a neural cooling probe to stop focal and spontaneous seizures by cooling the brain. The designed probe was composed of a U-shaped tube through which cold fluid flowed in order to reduce the temperature of the brain. The simulation results demonstrated that the neural probe could cool a 7 $mm^2$ area of the brain when the fluid was flowing atb a velocity of 0.55 m/s. It also showed that the neural cooling probe required 23 % less energy to produce cooling when compared to the Peltier chip-based cooling system.

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